Effect of pollution on DNA damage and essential fatty acid profile in Cirrhinus mrigala from River Chenab

Bilal Hussain; Tayyaba Sultana; Salma Sultana; K. A. Al-Ghanim; Shahid Mahboob

doi:10.1007/s00343-017-5304-5

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Effect of pollution on DNA damage and essential fatty acid profile in Cirrhinus mrigala from River Chenab

OriginalPaper | Updated：2023-05-16

- Effect of pollution on DNA damage and essential fatty acid profile in Cirrhinus mrigala from River Chenab
- Effect of pollution on DNA damage and essential fatty acid profile in Cirrhinus mrigala from River Chenab
- 海洋湖沼学报（英文） 2017年35卷第3期页码：572-579
- Affiliations：
  
  1. Department of Zoology Government College University
  2. Department of Zoology College of Science King Saud University
- Author bio：
- Funds：
  
  Supported by the Research Group Project of Deanship of Scientific Research at King Saud University (No. RG-1435-012)
- DOI：10.1007/s00343-017-5304-5
  中图分类号：
- 网络首发：2016-05-26，
  
  纸质出版：2017
- Accepted：
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Effect of pollution on DNA damage and essential fatty acid profile in Cirrhinus mrigala from River Chenab[J]. 海洋湖沼学报（英文）, 2017,35(3):572-579.

Hussain, B., Sultana, T., Sultana, S. et al. Effect of pollution on DNA damage and essential fatty acid profile in Cirrhinus mrigala from River Chenab., Chin. J. Ocean. Limnol. 35, 572–579 (2017). https://doi.org/10.1007/s00343-017-5304-5
Effect of pollution on DNA damage and essential fatty acid profile in Cirrhinus mrigala from River Chenab[J]. 海洋湖沼学报（英文）, 2017,35(3):572-579. DOI： 10.1007/s00343-017-5304-5.

Hussain, B., Sultana, T., Sultana, S. et al. Effect of pollution on DNA damage and essential fatty acid profile in Cirrhinus mrigala from River Chenab., Chin. J. Ocean. Limnol. 35, 572–579 (2017). https://doi.org/10.1007/s00343-017-5304-5 DOI：

摘要

Abstract

The objective of this study was to evaluate the effect of anthropogenic pollution on DNA damage and the fatty acid profile of the bottom dweller fish (Cirrhinus mrigala)

collected from the River Chenab

in order to assess the effect of the toxicants on the quality of the fish meat. The levels of Cd

Cr and Sn and of phenols from this river were significantly higher than the permissible limits set by the USEPA. Comet assays showed DNA damage in Cirrhinus mrigala collected from three different sampling sites in the polluted area of the river. Significant differences were observed for DNA damage through comet assay in fish collected from polluted compared to control sites. No significant differences were observed for DNA damage between farmed and fish collected from upstream. The micronucleus assay showed similar trends. Fish from the highly polluted sites showed less number of fatty acids and more saturated fatty acids in their meat compared to fish from less polluted areas. Several fatty acids were missing in fish with higher levels of DNA in comet tail and micronucleus induction. Long-chain polyunsaturated fatty acids

eicosapentaenoic acid (20:5n-3) was found missing in the fish from polluted environment while it was found in considerable amount in farmed fish 7.8±0.4%. Docosahexaenoic acid (22:6n-3) also showed significant differences as 0.1±0.0 and 7.0±0.1% respectively

in wild polluted and farmed fishes.

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references

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