Isolation, identification, and cytotoxicity of a new isobenzofuran derivative from marine Streptomyces sp. W007

Hongyu Zhang; Zeping Xie; Tingting Lou; Peng Jiang

doi:10.1007/s00343-015-4326-0

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Isolation, identification, and cytotoxicity of a new isobenzofuran derivative from marine Streptomyces sp. W007

OriginalPaper | Updated：2023-05-16

- Isolation, identification, and cytotoxicity of a new isobenzofuran derivative from marine Streptomyces sp. W007
- Isolation, identification, and cytotoxicity of a new isobenzofuran derivative from marine Streptomyces sp. W007
- 海洋湖沼学报（英文） 2016年34卷第2期页码：386-390
- Affiliations：
  
  1. Tianjin Key Laboratory of Food Biotechnology College of Biotechnology and Food Science Tianjin University of Commerce
  2. School of Pharmacy Binzhou Medical University
  3. Tianjin Entry & Exit Inspection and Quarantine Bureau
  4. Key Laboratory of Experimental Marine Biology Institute of Oceanology Chinese Academy of Sciences
- Author bio：
- Funds：
  
  Supported by the Open Fund of Key Laboratory of Experimental Marine Biology, Chinese Academy of Sciences (No. KF2015No07) and the Innovative and Entrepreneurial Training Program of College Students, Tianjin University of Commerce (No. 2015052)
- DOI：10.1007/s00343-015-4326-0
  中图分类号：
- 网络首发：2015-08-01，
  
  纸质出版：2016
- Accepted：
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Isolation, identification, and cytotoxicity of a new isobenzofuran derivative from marine Streptomyces sp. W007[J]. 海洋湖沼学报（英文）, 2016,34(2):386-390.

Zhang, H., Xie, Z., Lou, T. et al. Isolation, identification, and cytotoxicity of a new isobenzofuran derivative from marine Streptomyces sp. W007., Chin. J. Ocean. Limnol. 34, 386–390 (2016). https://doi.org/10.1007/s00343-015-4326-0
Isolation, identification, and cytotoxicity of a new isobenzofuran derivative from marine Streptomyces sp. W007[J]. 海洋湖沼学报（英文）, 2016,34(2):386-390. DOI： 10.1007/s00343-015-4326-0.

Zhang, H., Xie, Z., Lou, T. et al. Isolation, identification, and cytotoxicity of a new isobenzofuran derivative from marine Streptomyces sp. W007., Chin. J. Ocean. Limnol. 34, 386–390 (2016). https://doi.org/10.1007/s00343-015-4326-0 DOI：

摘要

Abstract

A new isobenzofuran derivative (1) was isolated from the marine Streptomyces sp. W007 and its structure was determined through extensive spectroscopic analyses

including 1D-NMR

2D-NMR

and ESI-MS. The absolute configuration of compound 1 was determined by a combination of experimental analyses and comparison with reported data

including biogenetic reasoning

J-coupling analysis

NOESY

and 1H-1HCOSY. Compound 1 exhibited no cytotoxicity against human cells of gastric cancer BGC-823

lung cancer A549

and breast cancer MCF7.

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references

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