Immune functional impacts of oyster peptide-based enteral nutrition formula (OPENF) on mice: a pilot study

Bingna Cai; Jianyu Pan; Yuantao Wu; Peng Wan; Huili Sun

doi:10.1007/s00343-013-2311-z

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Immune functional impacts of oyster peptide-based enteral nutrition formula (OPENF) on mice: a pilot study

OriginalPaper | Updated：2023-05-16

- Immune functional impacts of oyster peptide-based enteral nutrition formula (OPENF) on mice: a pilot study
- Immune functional impacts of oyster peptide-based enteral nutrition formula (OPENF) on mice: a pilot study
- 海洋湖沼学报（英文） 2013年31卷第4期页码：813-820
- Affiliations：
  
  1. Key Laboratory of Marine Bio-Resources Sustainable Utilization South China Sea Institute of Oceanology Chinese Academy of Sciences
  2. University of Chinese Academy of Sciences
  3. Bureau of Science and Technology for Resource and Environment Chinese Academy of Sciences
- Author bio：
- Funds：
  
  Supported by the Knowledge Innovation Program of Chinese Academy of Sciences (No. KZCX2-EW-Q214), the Comprehensive Strategic Cooperation Programs between Guangdong Province and Chinese Academy of Sciences (Nos. 2011A090100008, 2009B091300018, 2010B090300027), and the Marine Fisheries Technology PromotionSpecial Program of Guangdong Province (No. A2009009-035(a))
- DOI：10.1007/s00343-013-2311-z
  中图分类号：
- 网络首发：2013-07-10，
  
  纸质出版：2013
- Accepted：
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Immune functional impacts of oyster peptide-based enteral nutrition formula (OPENF) on mice: a pilot study[J]. 海洋湖沼学报（英文）, 2013,31(4):813-820.

Cai, B., Pan, J., Wu, Y. et al. Immune functional impacts of oyster peptide-based enteral nutrition formula (OPENF) on mice: a pilot study., Chin. J. Ocean. Limnol. 31, 813–820 (2013). https://doi.org/10.1007/s00343-013-2311-z
Immune functional impacts of oyster peptide-based enteral nutrition formula (OPENF) on mice: a pilot study[J]. 海洋湖沼学报（英文）, 2013,31(4):813-820. DOI： 10.1007/s00343-013-2311-z.

Cai, B., Pan, J., Wu, Y. et al. Immune functional impacts of oyster peptide-based enteral nutrition formula (OPENF) on mice: a pilot study., Chin. J. Ocean. Limnol. 31, 813–820 (2013). https://doi.org/10.1007/s00343-013-2311-z DOI：

摘要

Abstract

Oyster peptides were produced from Crassostrea hongkongensis and used as a new protein source for the preparation of an oyster peptide-based enteral nutrition formula (OPENF). Reserpineinduced malabsorption mice and cyclophosphamide-induced immunosuppression mice were used in this study. OPENF powder is light yellow green and has a protein-fat-carbohydrate ratio of 16:9:75 with good solubility in water. A pilot study investigating immune functional impacts of the OPENF on mice show that the OPENF enhanced spleen lymphocyte proliferation and the activity of natural killer (NK) cells in BALB/c mice. Furthermore

OPENF can improve intestinal absorption

increase food utilization ratio

and maintain the normal physiological function of mice. These results suggest that oyster peptides could serve as a new protein source for use in enteral nutrition formula

but more importantly

also indicate that OPENF has an immunostimulating effect in mice.

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references

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