A new ketosteroid from red alga Acanthophora spicifera

Dayong Shi; Shuju Guo; Xiao Fan

doi:10.1007/s00343-011-0183-7

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A new ketosteroid from red alga Acanthophora spicifera

OriginalPaper | Updated：2023-05-16

- A new ketosteroid from red alga Acanthophora spicifera
- A new ketosteroid from red alga Acanthophora spicifera
- 海洋湖沼学报（英文） 2011年29卷第3期页码：674-678
- Affiliations：
  
  Institute of Oceanology Chinese Academy of Sciences
- Author bio：
- Funds：
  
  Supported by the National Major Research Program of China “The Creation for Significant Innovative Drugs” (No. 2009ZX09103-148), and the Research and Development Program of Shinan District of Qingdao (No. 2009-2-14-HY)
- DOI：10.1007/s00343-011-0183-7
  中图分类号：
- 网络首发：2011-05-15，
  
  纸质出版：2011
- Accepted：
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A new ketosteroid from red alga Acanthophora spicifera[J]. 海洋湖沼学报（英文）, 2011,29(3):674-678.

Shi, D., Guo, S. & Fan, X. A new ketosteroid from red alga Acanthophora spicifera, ., Chin. J. Ocean. Limnol. 29, 674–678 (2011). https://doi.org/10.1007/s00343-011-0183-7
A new ketosteroid from red alga Acanthophora spicifera[J]. 海洋湖沼学报（英文）, 2011,29(3):674-678. DOI： 10.1007/s00343-011-0183-7.

Shi, D., Guo, S. & Fan, X. A new ketosteroid from red alga Acanthophora spicifera, ., Chin. J. Ocean. Limnol. 29, 674–678 (2011). https://doi.org/10.1007/s00343-011-0183-7 DOI：

摘要

Abstract

A new ketosteroid

along with six known steroids

was isolated from the ethanolic extracts of red alga Acanthophora spicifera (Vahl.) Boergesen. The structures

identified using chemical and spectroscopic methods including 2D NMR

were: (1) 22-hydroxy-5α-cholest-3

6-dione

(2) 6-hydroxycholest-4-ene-3-one

(3) cholest-4-ene-3

6-dione

(4) cholest-5-ene-3β-ol

(5) 5α-cholestane-3

6-dione

(6) β-Sitosterol and (7) Saringosterol. The MTT method was used to test the cytotoxicity of the compounds against the human cancer cell lines

HCT-8

Bel-7402

BGC-823

A549 and HELA. Compounds 1

3 and 5 showed moderate cytotoxic activity against human cancer cell lines.

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references

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