Proteomic aspects of infection by lymphocystis disease virus in Japanese flounder (Paralichthys olivaceus)

Mingqing Xing; Xiuqin Sun; Fengrong Zheng; Lingyun Qu; Xuguang Hong; Suqi Wu; Minggang Zheng; Jinxing Zhang

doi:10.1007/s00343-011-0060-4

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Proteomic aspects of infection by lymphocystis disease virus in Japanese flounder (Paralichthys olivaceus)

OriginalPaper | Updated：2023-05-16

- Proteomic aspects of infection by lymphocystis disease virus in Japanese flounder (Paralichthys olivaceus)
- Proteomic aspects of infection by lymphocystis disease virus in Japanese flounder (Paralichthys olivaceus)
- 海洋湖沼学报（英文） 2011年29卷第3期页码：603-608
- Affiliations：
  
  1. College of Marine Life Sciences Ocean University of China
  2. Department of Clinical Laboratory Qingdao Municipal Hospital
  3. The First Institute of Oceanography SOA
- Author bio：
- Funds：
  
  Supported by the National High Technology Research and Development Program of China (863 program)(No. 2006AA100309)
- DOI：10.1007/s00343-011-0060-4
  中图分类号：
- 网络首发：2011-05-15，
  
  纸质出版：2011
- Accepted：
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Proteomic aspects of infection by lymphocystis disease virus in Japanese flounder (Paralichthys olivaceus)[J]. 海洋湖沼学报（英文）, 2011,29(3):603-608.

Xing, M., Sun, X., Zheng, F. et al. Proteomic aspects of infection by lymphocystis disease virus in Japanese flounder (Paralichthys olivaceus)., Chin. J. Ocean. Limnol. 29, 603–608 (2011). https://doi.org/10.1007/s00343-011-0060-4
Proteomic aspects of infection by lymphocystis disease virus in Japanese flounder (Paralichthys olivaceus)[J]. 海洋湖沼学报（英文）, 2011,29(3):603-608. DOI： 10.1007/s00343-011-0060-4.

Xing, M., Sun, X., Zheng, F. et al. Proteomic aspects of infection by lymphocystis disease virus in Japanese flounder (Paralichthys olivaceus)., Chin. J. Ocean. Limnol. 29, 603–608 (2011). https://doi.org/10.1007/s00343-011-0060-4 DOI：

摘要

Abstract

To reveal the key factor in self-healing from LCDV (lymphocystis disease virus)-infected Japanese flounder (Paralichthys olivaceus)

serum proteins from self-healing and sick Japanese flounder were separated by two-dimensional electrophoresis to screen differentially expressed proteins. Protein spots demonstrating changes greater than two-fold in the expression level were digested and further identified in capillary liquid chromatography tandem mass spectrometry (LC-MS/MS). Two immunity-relevant proteins were thus identified as transferrin and the complement component C3 of Japanese flounder. These findings suggest that the two proteins may play important roles in the self-healing of lymphocystis in Japanese flounder. This is an important theoretical foundation to promote self-healing in LCDV-infected Japanese flounder by improving their innate immunity.

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references

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