Steroids from green alga Chaetomorpha basiretorsa Setchell
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Steroids from green alga Chaetomorpha basiretorsa Setchell
Steroids from green alga Chaetomorpha basiretorsa Setchell
海洋湖沼学报(英文)2008年26卷第4期 页码:415-418
Affiliations:
1. Institute of Oceanology Chinese Academy of Sciences
2. Institute of Materia Medica Chinese Academy of Medical Sciences and Peking Union Medical College
Author bio:
Funds:
Supported by High Technology Research and Development Program of China (863 Program) (No. 2007AA09Z410 and 2007AA091604), NSFC of China (No.30530080) and the Key Innovative Program, Chinese Academy of Sciences (No. KZCX2-YW-209).
Steroids from green alga Chaetomorpha basiretorsa Setchell[J]. 海洋湖沼学报(英文), 2008,26(4):415-418.
Shi, D., Fan, X., Sun, J. et al. Steroids from green alga Chaetomorpha basiretorsa Setchell., Chin. J. Ocean. Limnol. 26, 415–418 (2008). https://doi.org/10.1007/s00343-008-0415-7
Steroids from green alga Chaetomorpha basiretorsa Setchell[J]. 海洋湖沼学报(英文), 2008,26(4):415-418. DOI: 10.1007/s00343-008-0415-7.
Shi, D., Fan, X., Sun, J. et al. Steroids from green alga Chaetomorpha basiretorsa Setchell., Chin. J. Ocean. Limnol. 26, 415–418 (2008). https://doi.org/10.1007/s00343-008-0415-7DOI:
Steroids from green alga Chaetomorpha basiretorsa Setchell
摘要
Abstract
Six steroids have been isolated from ethanolic extract of green alga Chaetomorpha basiretorsa Setchell by a combination of repeated normal phase silica gel and Sephadex LH-20 gel column chromatography as well as recrystallization. Using spectroscopic methods including MS and NMR
their structures were determined as β-lawsaritol (1)
saringosterol (2)
24-hydroperoxy-24-vinyl-cholesterol (3)
β-stigmasterol (4)
stigmast-4-en-3α
6β-diol (5)
29-hydroxystigmasta-5
24 (28)-dien-3β-ol (6). All these compounds were obtained from this genus for the first time and they were inactive (IC50>10 μg /ml) against KB
Bel-7402
PC-3M
Ketr 3 and MCF-7 cell lines.
关键词
Keywords
references
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