Isolation and pharmacological activities of bromophenols fromRhodomela confervoides

Han Lijun; Xu Nianjun; Shi Jiangong; Yan Xiaojun; Zheng Chengkui

doi:10.1007/BF02894243

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Isolation and pharmacological activities of bromophenols fromRhodomela confervoides

OriginalPaper | Updated：2023-05-16

- Isolation and pharmacological activities of bromophenols fromRhodomela confervoides
- Isolation and pharmacological activities of bromophenols fromRhodomela confervoides
- 海洋湖沼学报（英文） 2005年23卷第2期页码：226-229
- Affiliations：
  
  1. Institute of Oceanology Chinese Academy of Sciences
  2. Institute of Marina Medica Chinese Academy of Medical Sciences
  3. Key Laboratory of Marine Biotechnology Ningbo University
- Author bio：
- Funds：
  
  Supported by National “863” Program (No. 2004AA625030, 2001AA620503), Quingdao marine sciences project (No. 04-2-NN-26) and Key Knowledge Innovative Project of the Chinese Academy of Sciences (KZCX3-SW-215).
- DOI：10.1007/BF02894243
  中图分类号：
- 纸质出版：2005
- Accepted：
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Isolation and pharmacological activities of bromophenols fromRhodomela confervoides[J]. 海洋湖沼学报（英文）, 2005,23(2):226-229.

Lijun, H., Nianjun, X., Jiangong, S. et al. Isolation and pharmacological activities of bromophenols fromRhodomela confervoides, ., Chin. J. Ocean. Limnol. 23, 226–229 (2005). https://doi.org/10.1007/BF02894243
Isolation and pharmacological activities of bromophenols fromRhodomela confervoides[J]. 海洋湖沼学报（英文）, 2005,23(2):226-229. DOI： 10.1007/BF02894243.

Lijun, H., Nianjun, X., Jiangong, S. et al. Isolation and pharmacological activities of bromophenols fromRhodomela confervoides, ., Chin. J. Ocean. Limnol. 23, 226–229 (2005). https://doi.org/10.1007/BF02894243 DOI：

摘要

Abstract

Four bromophenols were isolated from the extract of marine red alga

Rhodomela confervoides by column chromatography and HPLC methods. By means of spectroscopic methods inclding IR

and 2D-NMR techniques

their structures were elucidated as (1) 3-bromo-4

5-dihydroxy benzoic acid methyl ester; (2) bis (2

3-dibromo-4

5-dihydroxybenzyl) ether; (3) 3

4-dibromo-5-(methoxymethyl)-1

2-benzenediol and (4) 3-bromo-4

5-dihydroxy-benzaldehyde. Compound 1 was first isolated from the algae in nature

and 1

4 were found to have selective cytotoxic activities against KB

Bel 7402 and A549 cells

2 showed powerful antibacterial activities againstStaphylococcus aurens andPseudomonas aeruginosa.

关键词

Keywords

references

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