Effects of polypeptide fromChlamys farreri on amino acid content in guinea pig skin irradiated by chronic ultraviolet A and B

Yu Guoying; Cao Pengli; Guo Kun; Wang Yuejun; Sun Mi; Wang Chunbo

doi:10.1007/BF02843643

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Effects of polypeptide fromChlamys farreri on amino acid content in guinea pig skin irradiated by chronic ultraviolet A and B

OriginalPaper | Updated：2023-05-16

- Effects of polypeptide fromChlamys farreri on amino acid content in guinea pig skin irradiated by chronic ultraviolet A and B
- Effects of polypeptide fromChlamys farreri on amino acid content in guinea pig skin irradiated by chronic ultraviolet A and B
- 海洋湖沼学报（英文） 2004年22卷第4期页码：440-442
- Affiliations：
  
  Affiliated Hospital of Medical College Qingdao University
- Author bio：
- Funds：
  
  Project No. 39970638 supported by the NSFC, and also supported by the Science and Technology Bureau of Qingdao (No: 2001-28-50).
- DOI：10.1007/BF02843643
  中图分类号：
- 纸质出版：2004
- Accepted：
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Effects of polypeptide fromChlamys farreri on amino acid content in guinea pig skin irradiated by chronic ultraviolet A and B[J]. 海洋湖沼学报（英文）, 2004,22(4):440-442.

Guoying, Y., Pengli, C., Kun, G. et al. Effects of polypeptide fromChlamys farreri on amino acid content in guinea pig skin irradiated by chronic ultraviolet A and B., Chin. J. Ocean. Limnol. 22, 440–442 (2004). https://doi.org/10.1007/BF02843643
Effects of polypeptide fromChlamys farreri on amino acid content in guinea pig skin irradiated by chronic ultraviolet A and B[J]. 海洋湖沼学报（英文）, 2004,22(4):440-442. DOI： 10.1007/BF02843643.

Guoying, Y., Pengli, C., Kun, G. et al. Effects of polypeptide fromChlamys farreri on amino acid content in guinea pig skin irradiated by chronic ultraviolet A and B., Chin. J. Ocean. Limnol. 22, 440–442 (2004). https://doi.org/10.1007/BF02843643 DOI：

摘要

Abstract

We examined the effects of polypeptide fromChlamys farreri (PCF) on the amount of hydroxyproline in guinea pig skin irradiated by chronic ultraviolet A (UVA) and ultraviolet B (UVB) radiation. PCF was applied locally before repeated exposure of guinea pig to UVA and UVB. The contents of hydroxyproline and other amino acids in guinea pig skin were determined by automatic amino acid analyzer. Our results showed that: (1) long-time UVA and UVB radiation can reduce dramatically the amounts of hydroxyproline

aspartic acid

threonine

glycine

phenylalanine and lysine in guinea pig skin in comparison with the control group (P<0.05); (2) Compared with model group

pre-treatment with 5% and 20% PCF prior to UVA and UVB radiation can inhibit the decline of amino acids content in guinea pig skin in a dose-dependent manner (P<0.05). As the decrease of hydroxyproline

glycine and lysine contents in the skin directly reflexes type I collagen degeneration

our results indicated that the chronic application of PCF can protect skin type I collagen against UV radiation

and thus protect skin from photoaging.

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references

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