Disease resistance and humoral immunomodulatory effects of vitamin C on grouper,Epinephelus awoara

Qin Qi-wei; Wu Zao-he; Pan Jin-pei

doi:10.1007/BF02842671

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Disease resistance and humoral immunomodulatory effects of vitamin C on grouper,Epinephelus awoara

OriginalPaper | Updated：2023-05-16

- Disease resistance and humoral immunomodulatory effects of vitamin C on grouper,Epinephelus awoara
- Disease resistance and humoral immunomodulatory effects of vitamin C on grouper,Epinephelus awoara
- 海洋湖沼学报（英文） 2000年18卷第3期页码：247-252
- Affiliations：
  
  1. South China Sea Institute of Oceanology Chinese Academy of Sciences
  2. TMSI
- Author bio：
- Funds：
  
  Project 39500113 supported by NSFC and also by Guangdong Science Research Foundation (Grant No. 950711).
- DOI：10.1007/BF02842671
  中图分类号：
- 纸质出版：2000
- Accepted：
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Disease resistance and humoral immunomodulatory effects of vitamin C on grouper,Epinephelus awoara[J]. 海洋湖沼学报（英文）, 2000,18(3):247-252.

Qi-wei, Q., Zao-he, W. & Jin-pei, P. Disease resistance and humoral immunomodulatory effects of vitamin C on grouper,Epinephelus awoara, ., Chin. J. Ocean. Limnol. 18, 247–252 (2000). https://doi.org/10.1007/BF02842671
Disease resistance and humoral immunomodulatory effects of vitamin C on grouper,Epinephelus awoara[J]. 海洋湖沼学报（英文）, 2000,18(3):247-252. DOI： 10.1007/BF02842671.

Qi-wei, Q., Zao-he, W. & Jin-pei, P. Disease resistance and humoral immunomodulatory effects of vitamin C on grouper,Epinephelus awoara, ., Chin. J. Ocean. Limnol. 18, 247–252 (2000). https://doi.org/10.1007/BF02842671 DOI：

摘要

Abstract

The disease resistance and humoral immunomodulatory effects of vitamin C administered orally to grouper

Epinephelus awoara maintained on a frozen fish diet supplemented with vitamin C at 500

1000

1500 and 2000 mg/kg were investigated. After 20 weeks

the growth rates of the groups with high level of vitamin C apparently increased. The untreated fish had symptoms of vitamin C deficiency. The endogenous liver tissue vitamin C levels were found to reflect well the dietary treatments. After intraperitoneal injection or bath challenge with a virulent strain ofVibrio vulnificus

fish fed with high level vitamin C showed significantly higher survival rate compared with the normal control group. Vaccination with formalin inactivatedV. vulnificus significantly enhanced the specific antibody production in fish treated with vitamin C

and completely protected from strong bacterial challenge the groups fed on fish with vitamin C 1500 and 2000 mg/kg diet.

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references

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