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Department of Geriatric Internal Medicine Affiliated Hospital of Qingdao University
Online First:19 November 2015,
Published:2016
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Shi, S., Feng, W., Hu, S. et al. Bioactive compounds of sea cucumbers and their therapeutic effects., Chin. J. Ocean. Limnol. 34, 549–558 (2016). https://doi.org/10.1007/s00343-016-4334-8
Sea cucumbers belong to the Class Holothuroidea of marine invertebrates. They are commercially valuable and prized as a food and folk medicine in Asia. Nutritionally
sea cucumbers have an impressive profile of valuable nutrients such as vitamins
minerals and amino acids. A number of unique biological and pharmacological activities/properties
including anticancer
anticoagulant/antithrombotic
antimicrobial
antioxidant
antihyperlipidemic
antihyperglycemic
anti-inflammatory
antihypertension and radioprotective
have been ascribed to various compounds isolated from sea cucumbers. The therapeutic properties and medicinal benefits of sea cucumbers can be linked to the presence of a wide array of bioactives
especially triterpene glycosides
acid mucopolysaccharide
sphingoid bases
glycolipids
fucosylated chondroitin sulfate
polysaccharides
phospholipids
cerebrosides
phosphatidylcholines
and other extracts and hydrolysates. This review highlights the valuable bioactive components as well as the multiple therapeutic properties of sea cucumbers with a view to exploring their potential uses as functional foods and a natural source of new multifunctional drugs.
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