An outbreak of granulomatous inflammation associated with Francisella noatunensis subsp. orientalis in farmed tilapia (Oreochromis niloticus × O. aureus) in China

Qiang Lin; Ningqiu Li; Xiaozhe Fu; Qiandong Hu; Ouqin Chang; Lihui Liu; Defeng Zhang; Guangjun Wang; Guibao San; Shuqin Wu

doi:10.1007/s00343-016-4311-2

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An outbreak of granulomatous inflammation associated with Francisella noatunensis subsp. orientalis in farmed tilapia (Oreochromis niloticus × O. aureus) in China

Updated：2023-05-16

- An outbreak of granulomatous inflammation associated with Francisella noatunensis subsp. orientalis in farmed tilapia (Oreochromis niloticus × O. aureus) in China
- Journal of Oceanology and Limnology Vol. 34, Issue 3, Pages: 460-466(2016)
- Affiliations：
  
  1. Pearl River Fisheries Research Institute Chinese Academy of Fishery Sciences Key Laboratory of Fishery Drug Development Ministry of Agriculture Key Laboratory of Aquatic Animal Immune Technology
  2. Freshwater Aquaculture Collaborative Innovation Center of Hubei Province
  3. Panyu District Agricultural Science Research Institute
- Author bio：
- Funds：
- DOI：10.1007/s00343-016-4311-2
  CLC：
- Online First：21 October 2015，
  
  Published：2016
- Accepted：
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Lin, Q., Li, N., Fu, X. et al. An outbreak of granulomatous inflammation associated with Francisella noatunensis subsp. orientalis in farmed tilapia (Oreochromis niloticus × O. aureus) in China., Chin. J. Ocean. Limnol. 34, 460–466 (2016). https://doi.org/10.1007/s00343-016-4311-2
DOI：

Lin, Q., Li, N., Fu, X. et al. An outbreak of granulomatous inflammation associated with Francisella noatunensis subsp. orientalis in farmed tilapia (Oreochromis niloticus × O. aureus) in China., Chin. J. Ocean. Limnol. 34, 460–466 (2016). https://doi.org/10.1007/s00343-016-4311-2 DOI：

摘要

Abstract

In 2013

a novel disease was detected in tilapia (Oreochromis niloticus × O. aureus) in Guangzhou

South China. To identify the causative pathogen

we conducted histological examination

bacteria isolation

and purification

and sequenced the 16S rRNA gene of isolates. Infected fish had a large number of white granulomas in the kidney

liver

heart

and spleen. The head kidney and spleen were markedly swollen. A bacterium strain designated as gz201301 was recovered from the spleen of infected tilapia. The 16S rRNA sequence of gz201301 revealed that it was highly similar to F. noatunensis subsp. orientalis. This is the first report of a Francisella-like infection in farmed tilapia in China.

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references

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