Isolation, identification, and cytotoxicity of a new isobenzofuran derivative from marine Streptomyces sp. W007

Hongyu Zhang; Zeping Xie; Tingting Lou; Peng Jiang

doi:10.1007/s00343-015-4326-0

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Isolation, identification, and cytotoxicity of a new isobenzofuran derivative from marine Streptomyces sp. W007

Updated：2023-05-16

- Isolation, identification, and cytotoxicity of a new isobenzofuran derivative from marine Streptomyces sp. W007
- Journal of Oceanology and Limnology Vol. 34, Issue 2, Pages: 386-390(2016)
- Affiliations：
  
  1. Tianjin Key Laboratory of Food Biotechnology College of Biotechnology and Food Science Tianjin University of Commerce
  2. School of Pharmacy Binzhou Medical University
  3. Tianjin Entry & Exit Inspection and Quarantine Bureau
  4. Key Laboratory of Experimental Marine Biology Institute of Oceanology Chinese Academy of Sciences
- Author bio：
- Funds：
- DOI：10.1007/s00343-015-4326-0
  CLC：
- Online First：01 August 2015，
  
  Published：2016
- Accepted：
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Zhang, H., Xie, Z., Lou, T. et al. Isolation, identification, and cytotoxicity of a new isobenzofuran derivative from marine Streptomyces sp. W007., Chin. J. Ocean. Limnol. 34, 386–390 (2016). https://doi.org/10.1007/s00343-015-4326-0
DOI：

Zhang, H., Xie, Z., Lou, T. et al. Isolation, identification, and cytotoxicity of a new isobenzofuran derivative from marine Streptomyces sp. W007., Chin. J. Ocean. Limnol. 34, 386–390 (2016). https://doi.org/10.1007/s00343-015-4326-0 DOI：

摘要

Abstract

A new isobenzofuran derivative (1) was isolated from the marine Streptomyces sp. W007 and its structure was determined through extensive spectroscopic analyses

including 1D-NMR

2D-NMR

and ESI-MS. The absolute configuration of compound 1 was determined by a combination of experimental analyses and comparison with reported data

including biogenetic reasoning

J-coupling analysis

NOESY

and 1H-1HCOSY. Compound 1 exhibited no cytotoxicity against human cells of gastric cancer BGC-823

lung cancer A549

and breast cancer MCF7.

关键词

Keywords

references

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