Histopathological alterations in the liver and intestine of Nile tilapia Oreochromis niloticus exposed to long-term sublethal concentrations of cadmium chloride

Elsayed Younis; Abdel-Wahab Abdel-Warith; Nasser Al-Asgah; Hossam Ebaid

doi:10.1007/s00343-015-4082-1

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Histopathological alterations in the liver and intestine of Nile tilapia Oreochromis niloticus exposed to long-term sublethal concentrations of cadmium chloride

Updated：2023-05-16

- Histopathological alterations in the liver and intestine of Nile tilapia Oreochromis niloticus exposed to long-term sublethal concentrations of cadmium chloride
- Journal of Oceanology and Limnology Vol. 33, Issue 4, Pages: 846-852(2015)
- Affiliations：
  
  1. Department of Zoology College of Science King Saud University
  2. Department of Animal Production Faculty of Agriculture Al-Azhar University Nasr City
  3. Department of Zoology College of Science El-Minia University
- Author bio：
- Funds：
- DOI：10.1007/s00343-015-4082-1
  CLC：
- Online First：18 March 2015，
  
  Published：2015
- Accepted：
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Younis, E., Abdel-Warith, AW., Al-Asgah, N. et al. Histopathological alterations in the liver and intestine of Nile tilapia Oreochromis niloticus exposed to long-term sublethal concentrations of cadmium chloride., Chin. J. Ocean. Limnol. 33, 846–852 (2015). https://doi.org/10.1007/s00343-015-4082-1
DOI：

Younis, E., Abdel-Warith, AW., Al-Asgah, N. et al. Histopathological alterations in the liver and intestine of Nile tilapia Oreochromis niloticus exposed to long-term sublethal concentrations of cadmium chloride., Chin. J. Ocean. Limnol. 33, 846–852 (2015). https://doi.org/10.1007/s00343-015-4082-1 DOI：

摘要

Abstract

Fingerlings of Nile tilapia Oreochromis niloticus were exposed to 1.68

3.36

and 5.04 mg/L cadmium (as CdCl2)

which represent 10%

20%

and 30% of their previously determined 96-h LC50. After exposure for 20 days

sections of the liver and intestine of treated fish were examined histologically. Histopathological changes varied from slight to severe structural modification

depending on the exposure concentration. The hepatic tissues of fish exposed to 10% LC50 showed markedly increased vacuolation of the hepatocytes and coarse granulation of their cytoplasm. Abundant erythrocytic infiltration among the hepatocytes was observed in fish exposed to 20% LC50. In the intestinal tissues of fish exposed to all doses

goblet cells proliferated and were greatly increased in size

the longitudinal muscularis mucosa was disturbed and

in the crypts of the sub-mucosal layer

apoptosis increased

indicated by large numbers of degenerated nuclei. Large numbers of inflammatory cells and dilated blood vessels were observed in the intestine of the group treated with 30% LC50.

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Keywords

references

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