Effect of cadmium on the defense response of Pacific oyster Crassostrea gigas to Listonella anguillarum challenge

Ming Cong; Jiasen Lü; Huifeng Wu; Jianmin Zhao

doi:10.1007/s00343-013-2280-2

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Effect of cadmium on the defense response of Pacific oyster Crassostrea gigas to Listonella anguillarum challenge

Updated：2023-05-16

- Effect of cadmium on the defense response of Pacific oyster Crassostrea gigas to Listonella anguillarum challenge
- Journal of Oceanology and Limnology Vol. 31, Issue 5, Pages: 1002-1009(2013)
- Affiliations：
  
  1. Key Laboratory of Coastal Zone Environment Processes Chinese Academy of Sciences
  2. Shandong Provincial Key Laboratory of Coastal Zone Environment Processes Yantai Institute of Coastal Zone Research Chinese Academy of Sciences
  3. Biology School of Yantai University
- Author bio：
- Funds：
- DOI：10.1007/s00343-013-2280-2
  CLC：
- Online First：07 September 2013，
  
  Published：2013
- Accepted：
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Cong, M., Lü, J., Wu, H. et al. Effect of cadmium on the defense response of Pacific oyster Crassostrea gigas to Listonella anguillarum challenge., Chin. J. Ocean. Limnol. 31, 1002–1009 (2013). https://doi.org/10.1007/s00343-013-2280-2
DOI：

Cong, M., Lü, J., Wu, H. et al. Effect of cadmium on the defense response of Pacific oyster Crassostrea gigas to Listonella anguillarum challenge., Chin. J. Ocean. Limnol. 31, 1002–1009 (2013). https://doi.org/10.1007/s00343-013-2280-2 DOI：

摘要

Abstract

Heavy metal pollution can affect the immune capability of organisms. We evaluated the effect of cadmium (Cd) on the defense responses of the Pacific oyster Crassostrea gigas to Listonella anguillarum challenge. The activities of several important defensive enzymes

including superoxide dismutase (SOD)

glutathione peroxidase (GPx)

acid phosphatase (ACP)

Na+

K+ -ATPase in gills and hepatopancreas

and phenoloxidase-like (POL) enzyme in hemolymph were assayed. In addition

the expression levels of several genes

including heat shock protein 90 (HSP90)

metallothionein (MT)

and bactericidal/permeability increasing (BPI) protein were quantified by fluorescent quantitative PCR. The enzyme activities of SOD

ACP

POL

and GPx in hepatopancreas

and the expression of HSP90 were down-regulated

whereas GPx activity in the gill

Na+

K+-ATPase activities in both tissues

and MT expression was increased in Cdexposed oysters post L. anguillarum challenge. However

BPI expression was not significantly altered by co-stress of L. anguillarum infection and cadmium exposure. Our results suggest that cadmium exposure alters the oysters’ immune responses and energy metabolism following vibrio infection.

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references

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