Tissue-specific bioaccumulation and oxidative stress responses in juvenile Japanese flounder (Paralichthys olivaceus) exposed to mercury

Wei Huang; Liang Cao; Zhenjiang Ye; Longshan Lin; Quanzhen Chen; Shuozeng Dou

doi:10.1007/s00343-012-1210-z

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Tissue-specific bioaccumulation and oxidative stress responses in juvenile Japanese flounder (Paralichthys olivaceus) exposed to mercury

Updated：2023-05-16

- Tissue-specific bioaccumulation and oxidative stress responses in juvenile Japanese flounder (Paralichthys olivaceus) exposed to mercury
- Journal of Oceanology and Limnology Vol. 30, Issue 4, Pages: 569-579(2012)
- Affiliations：
  
  1. Laboratory of Marine Ecosystem and Biogeochemistry Second Institute of Oceanography State Oceanic Administration
  2. Key Laboratory of Marine Ecology and Environmental Sciences Institute of Oceanology Chinese Academy of Sciences
  3. Fishery College Ocean University of China
  4. Third Institute of Oceanography State Oceanic Administration
- Author bio：
- Funds：
- DOI：10.1007/s00343-012-1210-z
  CLC：
- Online First：02 July 2012，
  
  Published：2012
- Accepted：
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Huang, W., Cao, L., Ye, Z. et al. Tissue-specific bioaccumulation and oxidative stress responses in juvenile Japanese flounder (Paralichthys olivaceus) exposed to mercury., Chin. J. Ocean. Limnol. 30, 569–579 (2012). https://doi.org/10.1007/s00343-012-1210-z
DOI：

Huang, W., Cao, L., Ye, Z. et al. Tissue-specific bioaccumulation and oxidative stress responses in juvenile Japanese flounder (Paralichthys olivaceus) exposed to mercury., Chin. J. Ocean. Limnol. 30, 569–579 (2012). https://doi.org/10.1007/s00343-012-1210-z DOI：

摘要

Abstract

To understand mercury (Hg) toxicity in marine fish

we measured Hg accumulation in juvenile Japanese flounder (Paralichthys olivaceus) and assessed the effects on growth and antioxidant responses. After Hg exposure (control

and 160 μg/L Hg) for 28 d

fish growth was significantly reduced. The accumulation of Hg in fish was dose-dependent and tissue-specific

with the maximum accumulation in kidney and liver

followed by gills

bone

and muscle. Different antioxidants responded differently to Hg exposure to cope with the induction of lipid peroxidation (LPO)

which was also tissue-specific and dosedependent. As Hg concentration increased

superoxide dismutase (SOD) and catalase (CAT) activities increased significantly

whereas glutathione S -transferase (GST) activity and glutathione (GSH) levels decreased significantly in the gills. SOD and glutathione peroxidase (GPx) activities and the GSH level increased significantly in the liver. SOD activity and GSH levels increased significantly

but CAT activity decreased significantly with an increase in Hg concentration in the kidney. LPO was induced significantly by elevated Hg in the gills and kidney but was least affected in the liver. Therefore

oxidative stress biomarkers in gills were more sensitive than those in the liver and kidney to Hg exposure. Thus

the gills have potential as bioindicators for evaluating Hg toxicity in juvenile flounder.

关键词

Keywords

references

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