A new ketosteroid from red alga Acanthophora spicifera

Dayong Shi; Shuju Guo; Xiao Fan

doi:10.1007/s00343-011-0183-7

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A new ketosteroid from red alga Acanthophora spicifera

Updated：2023-05-16

- A new ketosteroid from red alga Acanthophora spicifera
- Journal of Oceanology and Limnology Vol. 29, Issue 3, Pages: 674-678(2011)
- Affiliations：
  
  Institute of Oceanology Chinese Academy of Sciences
- Author bio：
- Funds：
- DOI：10.1007/s00343-011-0183-7
  CLC：
- Online First：15 May 2011，
  
  Published：2011
- Accepted：
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Shi, D., Guo, S. & Fan, X. A new ketosteroid from red alga Acanthophora spicifera, ., Chin. J. Ocean. Limnol. 29, 674–678 (2011). https://doi.org/10.1007/s00343-011-0183-7
DOI：

Shi, D., Guo, S. & Fan, X. A new ketosteroid from red alga Acanthophora spicifera, ., Chin. J. Ocean. Limnol. 29, 674–678 (2011). https://doi.org/10.1007/s00343-011-0183-7 DOI：

摘要

Abstract

A new ketosteroid

along with six known steroids

was isolated from the ethanolic extracts of red alga Acanthophora spicifera (Vahl.) Boergesen. The structures

identified using chemical and spectroscopic methods including 2D NMR

were: (1) 22-hydroxy-5α-cholest-3

6-dione

(2) 6-hydroxycholest-4-ene-3-one

(3) cholest-4-ene-3

6-dione

(4) cholest-5-ene-3β-ol

(5) 5α-cholestane-3

6-dione

(6) β-Sitosterol and (7) Saringosterol. The MTT method was used to test the cytotoxicity of the compounds against the human cancer cell lines

HCT-8

Bel-7402

BGC-823

A549 and HELA. Compounds 1

3 and 5 showed moderate cytotoxic activity against human cancer cell lines.

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Keywords

references

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