Enzyme responses and lipid peroxidation in gills and hepatopancreas of clam Mactra vereformis, following cadmium exposure

Xiaoyu Wang; Hongsheng Yang; Guangbin Liu; Qing Wang

doi:10.1007/s00343-011-0088-5

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Enzyme responses and lipid peroxidation in gills and hepatopancreas of clam Mactra vereformis, following cadmium exposure

Updated：2023-05-16

- Enzyme responses and lipid peroxidation in gills and hepatopancreas of clam Mactra vereformis, following cadmium exposure
- Journal of Oceanology and Limnology Vol. 29, Issue 5, Pages: 981-989(2011)
- Affiliations：
  
  1. Key Laboratory of Marine Ecology and Environmental Sciences Institute of Oceanology Chinese Academy of Sciences
  2. Tianjin Fisheries Research Institute
  3. Mariculture Institute of Shandong Province
- Author bio：
- Funds：
- DOI：10.1007/s00343-011-0088-5
  CLC：
- Online First：08 August 2011，
  
  Published：2011
- Accepted：
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Wang, X., Yang, H., Liu, G. et al. Enzyme responses and lipid peroxidation in gills and hepatopancreas of clam Mactra vereformis, following cadmium exposure., Chin. J. Ocean. Limnol. 29, 981–989 (2011). https://doi.org/10.1007/s00343-011-0088-5
DOI：

Wang, X., Yang, H., Liu, G. et al. Enzyme responses and lipid peroxidation in gills and hepatopancreas of clam Mactra vereformis, following cadmium exposure., Chin. J. Ocean. Limnol. 29, 981–989 (2011). https://doi.org/10.1007/s00343-011-0088-5 DOI：

摘要

Abstract

To assess the toxicity of heavy metal pollution to marine intertidal shellfish

enzymatic responses and lipid peroxidation were investigated in the clam Mactra vereformis exposed to cadmium under laboratory conditions. Three antioxidant enzymes (superoxide dismutase

SOD; catalase

CAT; glutathione peroxidase

GPx)

two immune defense enzymes (acid phosphatase

ACP; alkaline phosphatase

ALP)

and one lipid peroxidation product (malondialdehyde

MDA) were measured in the gills and the hepatopancreas of the clam exposed to 0

and 125 μg/L cadmium for 0

and 7 d. The results show that the concentrations of antioxidant enzymes in the organs soared to a peak value on the first day and then decreased afterwards in most cases. CAT and GPx activities in the hepatopancreas were higher than in the gills

but the SOD activity was lower in the hepatopancreas. ACP activity was unchanged until Day 3 in the hepatopancreas and until Day 5 in gills

when it began to increase. ALP activity showed no significant relationship with Cd treatment. MDA concentrations increased in the two tissues after Cd exposure

peaked on Day 3 in gills

and on Day 5 in hepatopancreas. These observations show that changes in the activities of antioxidant enzymes and ACP reflect the time course of oxidative stress in the clam caused by Cd

and could be used as potential biomarkers for ecotoxicological bioassays of heavy metals.

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references

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