Variations of antioxidant enzyme activity and malondialdehyde content in nemertean Cephalothrix hongkongiensis after exposure to heavy metals

Haiyi Wu; Xidan Zhao; Shichun Sun

doi:10.1007/s00343-010-9050-1

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Variations of antioxidant enzyme activity and malondialdehyde content in nemertean Cephalothrix hongkongiensis after exposure to heavy metals

Updated：2023-05-16

- Variations of antioxidant enzyme activity and malondialdehyde content in nemertean Cephalothrix hongkongiensis after exposure to heavy metals
- Journal of Oceanology and Limnology Vol. 28, Issue 4, Pages: 917-923(2010)
- Affiliations：
  
  1. Marine Culture Research Laboratory Ocean University of China
  2. College of Marine Life Sciences Ocean University of China
- Author bio：
- Funds：
- DOI：10.1007/s00343-010-9050-1
  CLC：
- Online First：29 June 2010，
  
  Published：2010
- Accepted：
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Wu, H., Zhao, X. & Sun, S. Variations of antioxidant enzyme activity and malondialdehyde content in nemertean Cephalothrix hongkongiensis after exposure to heavy metals., Chin. J. Ocean. Limnol. 28, 917–923 (2010). https://doi.org/10.1007/s00343-010-9050-1
DOI：

Wu, H., Zhao, X. & Sun, S. Variations of antioxidant enzyme activity and malondialdehyde content in nemertean Cephalothrix hongkongiensis after exposure to heavy metals., Chin. J. Ocean. Limnol. 28, 917–923 (2010). https://doi.org/10.1007/s00343-010-9050-1 DOI：

摘要

Abstract

The antioxidant enzyme activity and malondialdehyde (MDA) content of Cephalothrix hongkongiensis were studied to assess variations in the biochemical/physiological parameters of nemerteans under heavy metal stress. Worms were exposed to copper

zinc and cadmium solutions at different concentrations

and the activity of three antioxidant enzymes

catalase (CAT)

superoxide dismutase (SOD)

and glutathione peroxidase (GPX)

and MDA content were measured. The results show that the activity of each enzyme changed immediately after exposure to heavy metals. CAT was invariably inhibited throughout the experimental period

while the SOD activity was significantly elevated by exposure to Cu2+ for 48 h

but then decreased. SOD was inhibited by Zn2+during the first 12 h of exposure

but activated when exposed for longer periods. Under Cd2+ stress

SOD activity decreased within 72 h. GPX activity varied greatly

being significantly increased by both Cu2+ and Zn2+

but significantly inhibited by Cd2+ in the first 12–24 h after exposure. MDA content increased on Cu2+ exposure

but normally decreased on Zn2+ exposure. MDA content followed an increase-decrease-increase pattern under Cd2+ stress. In conclusion

the antioxidant system of this nemertean is sensitive to heavy metals

and its CAT activity may be a potential biomarker for monitoring heavy metal levels in the environment.

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references

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