Chemical constituents of marine medicinal mangrove plant Sonneratia caseolaris
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Chemical constituents of marine medicinal mangrove plant Sonneratia caseolaris
Journal of Oceanology and LimnologyVol. 27, Issue 2, Pages: 288-296(2009)
Affiliations:
1. Key Laboratory of Experimental Marine Biology Institute of Oceanology Chinese Academy of Sciences
2. Graduate School of Chinese Academy of Sciences
3. State Key Laboratory of Tropical Crops Biotechnology Institute of Tropical Bioscience and Biotechnology Chinese Academy of Tropical Agriculture Sciences
Tian, M., Dai, H., Li, X. et al. Chemical constituents of marine medicinal mangrove plant Sonneratia caseolaris, ., Chin. J. Ocean. Limnol. 27, 288–296 (2009). https://doi.org/10.1007/s00343-009-9138-7
DOI:
Tian, M., Dai, H., Li, X. et al. Chemical constituents of marine medicinal mangrove plant Sonneratia caseolaris, ., Chin. J. Ocean. Limnol. 27, 288–296 (2009). https://doi.org/10.1007/s00343-009-9138-7DOI:
Chemical constituents of marine medicinal mangrove plant Sonneratia caseolaris
摘要
Abstract
Twenty-four compounds including eight steroids (1–8)
nine triterpenoids (9–16
24)
three flavonoids (20–22)
and four benzenecarboxylic derivatives (17–19
23) were isolated and identified from stems and twigs of medicinal mangrove plant Sonneratia caseolaris. The structures of the isolated compounds were determined by extensive analysis of their spectroscopic data. Among these metabolites
compounds 1
4–20 and 22–24 were isolated and identified for the first time from S. caseolaris. In the in vitro cytotoxic assay against SMMC-7721 human hepatoma cells
compound 21 (3′
4′
5
7-tetrahydroxyflavone) exhibited significant activity with IC50 2.8 μg/mL
while oleanolic acid (14)
3
3′-di-O-methyl ether ellagic acid (18)
and 3
3′
4-O-tri-O-methyl ether ellagic acid (19) showed weak activity. None of these compounds displayed significant antibacterial activites.
关键词
Keywords
references
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