Accumulation and depuration of pectenotoxins in brown crab Cancer pagurus

Li Zhaoxin

doi:10.1007/s00343-009-9109-z

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Accumulation and depuration of pectenotoxins in brown crab Cancer pagurus

Updated：2023-05-16

- Accumulation and depuration of pectenotoxins in brown crab Cancer pagurus
- Journal of Oceanology and Limnology Vol. 27, Issue 2, Pages: 389-394(2009)
- Affiliations：
  
  1. Yellow Sea Fishery Research Institute
  2. Food technology college Ocean University of China
  3. Norwegian School of Veterinary Science
- Author bio：
- Funds：
- DOI：10.1007/s00343-009-9109-z
  CLC：
- Online First：12 July 2009，
  
  Published：2009
- Accepted：
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Zhaoxin, L. Accumulation and depuration of pectenotoxins in brown crab Cancer pagurus, ., Chin. J. Ocean. Limnol. 27, 389–394 (2009). https://doi.org/10.1007/s00343-009-9109-z
DOI：

Zhaoxin, L. Accumulation and depuration of pectenotoxins in brown crab Cancer pagurus, ., Chin. J. Ocean. Limnol. 27, 389–394 (2009). https://doi.org/10.1007/s00343-009-9109-z DOI：

摘要

Abstract

Pectenotoxins (PTXs) are a group of marine algal toxins. In this study

the accumulation and depuration of pectenotoxins in brown crab Cancer pagurus were investigated. Crabs were fed with toxic blue mussels Mytilus edulis for 21 days and then depurated for 42 days. Toxins were extracted with methanol from the digestive glands of contaminated crabs

uncontaminated crabs (control group) and from blue mussels for comparison. Extracts were analyzed by liquid chromatograph coupled with tandem mass spectrometry (LC-MS-MS). The concentrations of PTX-2

PTX-2 SA

7-epi-PTX-2 SA

and PTX-12 were analyzed in two batches of toxic blue mussels and the crabs. A one-compartment model was applied to describe the depuration of PTXs. The half-life of PTXs was estimated to be 6–7.5 days. After depuration for 42 days

the amount of PTXs measured in the crab digestive glands was less than 1 μg/kg.

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references

Arakawa, O., S. Nishio, T. Noguchi, Y. Shida and Y. Onoue, 1995. A new saxitoxin analogue from a xanthid crab Atergatis floridus. Toxicon 33(12): 1 577–1 584.

Blanco, J., G. Alvarez and E. Uribe, 2007. Identification of pectenotoxins in plankton, filter feeders, and isolated cells of a Dinophysis acuminata with an atypical toxin profile, from Chile. Toxicon 49(5): 710–716.

Castberg, T., T. Torgersen, J. Aasen, T. Aune and L. J. Naustvoll, 2004. Diarrhoetic shellfish poisoning toxins in Cancer pagurus Linnaeus, 1758 (Brachyura, Cancridae) in Norwegian waters. Sarsia 89(5): 311–317.

Costa, P. R., S. M. Rodrigues, M. J. Botelho and M. A. D. Sampayo, 2003. A potential vector of domoic acid: the swimming crab Polybius henslowii Leach (Decapoda-brachyura). Toxicon 42(2): 135–141.

Daiguji, M., M. Satake, K. J. James, A. Bishop, L. MacKenzie, H. Naoki and T. Yasumoto, 1998. Structures of new pectenotoxin analogs, pectenotoxin-2 seco acid and 7-epi-pectenotoxin-2 seco acid, isolated from a dinoflagellate and greenshell mussels. Chemistry Letters 7: 653–654.

Draisci, R., L. Lucentini, L. Giannetti, P. Boria and R. Poletti, 1996. First report of pectenotoxin-2 (PTX-2) in algae (Dinophysis fortii) related to seafood poisoning in Europe. Toxicon 34(8): 923–935.

Fernandez, M. L., B. Reguera, S. Gonzalez-Gil and A. Miguez, 2006. Pectenotoxin-2 in single-cell isolates of Dinophysis caudata and Dinophysis acuta from the Galician Rias (NW Spain). Toxicon 48(5): 477–490.

James, K. J., A. G. Bishop, R. Draisci, L. Palleschi, C. Marchiafava, E. Ferretti, M. Satake and T. Yasumoto, 1999. Liquid chromatographic methods for the isolation and identification of new pectenotoxin-2 analogues from marine phytoplankton and shellfish. J. Chromatogr. A 844(1–2): 53–65.

Klaassen, C. D., 1996. Casarett & Doull’s Toxicology: The Basic Science of Poisons. McGraw-Hill, New York. p. 187–193.

MacKenzie, L., P. Holland, P. McNabb, V. Beuzenberg, A. Selwood and T. Suzuki, 2002. Complex toxin profiles in phytoplankton and Greenshell mussels (Perna canaliculus), revealed by LC-MS/MS analysis. Toxicon 40(9): 1 321–1 330.

MacKenzie, L., V. Beuzenberg, P. Holland, P. McNabb, T. Suzuki and A. Selwood, 2005. Pectenotoxin and okadaic acid-based toxin profiles in Dinophysis acuta and Dinophysis acuminata from New Zealand. Harmful Algae 4(1): 75–85.

Madigan, T. L., K. G. Lee, D. J. Padula, P. McNabb and A. M. Pointon, 2006. Diarrhetic shellfish poisoning (DSP) toxins in South Australian shellfish. Harmful Algae 5(2): 119–123.

Miles, C. O., 2007. Pectenotoxins. In: Botana, L. M. ed. Phycotoxins: Chemistry and Biochemistry. Wiley-Blackwell Publishing Ltd, Oxford. p. 159–186.

Miles, C. O., A. L. Wilkins, A. D. Hawkes, D. J. Jensen, A. I. Selwood, V. Beuzenberg, A. Lincoln MacKenzie, J. M. Cooney and P. T. Holland, 2006. Isolation and identification of pectenotoxins-13 and -14 from Dinophysis acuta in New Zealand. Toxicon 48(2): 152–159.

Miles, C. O., A. L. Wilkins, R. Munday, M. H. Dines, A. D. Hawkes and L. R. Briggs, 2004. Isolation of pectenotoxin-2 from Dinophysis acuta and its conversion to pectenotoxin-2 seco acid, and preliminary assessment of their acute toxicities. Toxicon 43(1): 1–9.

Oikawa, H., M. Satomi, S. Watabe and Y. Yano, 2005. Accumulation and depuration rates of paralytic shellfish poisoning toxins in the shore crab Telmessus acutidens by feeding toxic mussels under laboratory controlled conditions. Toxicon 45(2): 163–169.

Oikawa, H., T. Fujita, M. Satomi, T. Suzuki, Y. Kotani and Y. Yano, 2002. Accumulation of paralytic shellfish poisoning toxins in the edible shore crab Telmessus acutidens. Toxicon 40(11):1 593–1 599.

Quilliam, M. A. and P. C. Hess, 2001. Recent development in the analysis of phycotoxins by liquid chromatogrphy-mass spectrometry. In: De Koe, W. J., R. A. Samson, H. P. van Egmond, J. Gilbert, M. Sabino, eds. Mycotoxins and Phycotoxins in Perspective at the Turn of the Millenium Proceedings of the Xth International IUPAC Symposium on mycotoxins and phycotoxins. Ponsen & Looijen, Netherlands. p. 383–391.

Suzuki, T., T. Mitsuya, H. Matsubara and M. Yamasaki, 1998. Determination of pectenotoxin-2 after solid-phase extraction from seawater and from the dinoflagellate Dinophysis fortii by liquid chromatography with electrospray mass spectrometry and ultraviolet detection: Evidence of oxidation of pectenotoxin-2 to pectenotoxin-6 in scallops. J. Chromatogr. A 815(1): 155–160.

Suzuki, T., V. Beuzenberg, L. MacKenzie and M. A. Quilliam, 2003. Liquid chromatography-mass spectrometry of spiroketal stereoisomers of pectenotoxins and the analysis of novel pectenotoxin isomers in the toxic dinoflagellate Dinophysis acuta from New Zealand. J. Chromatogr. A 992(1–2): 141–150.

Torgersen, T., J. Aasen and T. Aune, 2005. Diarrhetic shellfish poisoning by okadaic acid esters from Brown crabs (Cancer pagurus) in Norway. Toxicon 46(5): 572–578.

Vale, P. and M. A. D. Sampayo, 2002a. Pectenotoxin-2 seco acid, 7-epi-pectenotoxin-2 seco acid and pectenotoxin-2 in shellfish and plankton from Portugal. Toxicon 40(7): 979–987.

Vale, P. and M. A. D. Sampayo, 2002b. First confirmation of human diarrhoeic poisonings by okadaic acid esters after ingestion of razor clams (Solen marginatus) and green crabs (Carcinus maenas) in Aveiro lagoon, Portugal and detection of okadaic acid esters in phytoplankton. Toxicon 40(7): 989–996.

Vale, P., 2004. Differential dynamics of dinophysistoxins and pectenotoxins between blue mussel and common cockle: a phenomenon originating from the complex toxin profile of Dinophysis acuta. Toxicon 44(2): 123–134.

Walter, J. A., M. Falk and J. L. C. Wright, 1994. Chemistry of the shellfish toxin Domoic Acid — Characterization of related-compounds. Can. J. Chem./Rev. Can. Chim. 72(2): 430–436.

Wilkins, A. L., N. Rehmann, T. Torgersen, T. Rundberget, M. Keogh, D. Petersen, P. Hess, F. Rise and C. O. Miles, 2006. Identification of fatty acid esters of pectenotoxin-2 seco acid in blue mussels (Mytilus edulis) from Ireland. J. Agric. Food Chem. 54(15): 5 672–5 678.

Yasumoto, T., M. Murata, Y. Oshima, M. Sano, G. K. Matsumoto and J. Clardy, 1985. Diarrhetic shellfish toxins. Tetrahedron 41(6): 1 019–1 025.

Yasumoto, T., Y. Oshima and Y. Kotaki, 1983. Analysis of paralytic shellfish toxins in coral reef crabs and gastropods with the identification of the primary source of toxins. Toxicon 21(Supplement 3): 513–516.

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