The chemical constituents from red alga Gymnogongrus flabelliformis Harv.

Zhaohui Yuan; Lijun Han; Hua Su; Dayong Shi; Jie Sun; Shuai Li; Jiangong Shi

doi:10.1007/s00343-008-0190-5

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The chemical constituents from red alga Gymnogongrus flabelliformis Harv.

Updated：2023-05-16

- The chemical constituents from red alga Gymnogongrus flabelliformis Harv.
- Journal of Oceanology and Limnology Vol. 26, Issue 2, Pages: 190-192(2008)
- Affiliations：
  
  1. Institute of Oceanology Chinese Academy of Sciences
  2. Graduate School of Chinese Academy of Sciences
  3. Institute of Materia Medica Chinese Academy of Medical Sciences and Peking Union Medical College
- Author bio：
- Funds：
- DOI：10.1007/s00343-008-0190-5
  CLC：
- Online First：28 May 2008，
  
  Published：2008
- Accepted：
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Yuan, Z., Han, L., Su, H. et al. The chemical constituents from red alga Gymnogongrus flabelliformis Harv.., Chin. J. Ocean. Limnol. 26, 190–192 (2008). https://doi.org/10.1007/s00343-008-0190-5
DOI：

Yuan, Z., Han, L., Su, H. et al. The chemical constituents from red alga Gymnogongrus flabelliformis Harv.., Chin. J. Ocean. Limnol. 26, 190–192 (2008). https://doi.org/10.1007/s00343-008-0190-5 DOI：

摘要

Abstract

Eight compounds were isolated from red alga Gymnogongrus flabelliformis Harv. In normal phase silica gel

Sephadex LH-20 gel column chromatography

reverse phase HPLC

and recrystallization. Based on MS and 1D NMR spectroscopic data

their structures were determined as: stigmast-4-en-3-one (I)

cholest-4-en-3-one (II)

cholesterol (III)

uracil (IV)

uridine (V)

adenosine (VI)

succinic acid (VII)

and 5-hydroxy-4-methyl-5-pentyl-2

5-dihydro-furan-2-on (VIII). All of them were obtained from this species for the first time. Cytotoxicity of these compounds was screened using standard MTT method

but all the compounds were inactive (IC50 > 10 μg/ml).

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references

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