Isolation and pharmacological activities of bromophenols fromRhodomela confervoides

Han Lijun; Xu Nianjun; Shi Jiangong; Yan Xiaojun; Zheng Chengkui

doi:10.1007/BF02894243

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Isolation and pharmacological activities of bromophenols fromRhodomela confervoides

Updated：2023-05-16

- Isolation and pharmacological activities of bromophenols fromRhodomela confervoides
- Journal of Oceanology and Limnology Vol. 23, Issue 2, Pages: 226-229(2005)
- Affiliations：
  
  1. Institute of Oceanology Chinese Academy of Sciences
  2. Institute of Marina Medica Chinese Academy of Medical Sciences
  3. Key Laboratory of Marine Biotechnology Ningbo University
- Author bio：
- Funds：
- DOI：10.1007/BF02894243
  CLC：
- Published：2005
- Accepted：
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Lijun, H., Nianjun, X., Jiangong, S. et al. Isolation and pharmacological activities of bromophenols fromRhodomela confervoides, ., Chin. J. Ocean. Limnol. 23, 226–229 (2005). https://doi.org/10.1007/BF02894243
DOI：

Lijun, H., Nianjun, X., Jiangong, S. et al. Isolation and pharmacological activities of bromophenols fromRhodomela confervoides, ., Chin. J. Ocean. Limnol. 23, 226–229 (2005). https://doi.org/10.1007/BF02894243 DOI：

摘要

Abstract

Four bromophenols were isolated from the extract of marine red alga

Rhodomela confervoides by column chromatography and HPLC methods. By means of spectroscopic methods inclding IR

and 2D-NMR techniques

their structures were elucidated as (1) 3-bromo-4

5-dihydroxy benzoic acid methyl ester; (2) bis (2

3-dibromo-4

5-dihydroxybenzyl) ether; (3) 3

4-dibromo-5-(methoxymethyl)-1

2-benzenediol and (4) 3-bromo-4

5-dihydroxy-benzaldehyde. Compound 1 was first isolated from the algae in nature

and 1

4 were found to have selective cytotoxic activities against KB

Bel 7402 and A549 cells

2 showed powerful antibacterial activities againstStaphylococcus aurens andPseudomonas aeruginosa.

关键词

Keywords

references

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