Effects of polypeptide fromChlamys farreri on amino acid content in guinea pig skin irradiated by chronic ultraviolet A and B

Yu Guoying; Cao Pengli; Guo Kun; Wang Yuejun; Sun Mi; Wang Chunbo

doi:10.1007/BF02843643

Your Location：

Home >

Browse articles >

Effects of polypeptide fromChlamys farreri on amino acid content in guinea pig skin irradiated by chronic ultraviolet A and B

Updated：2023-05-16

- Effects of polypeptide fromChlamys farreri on amino acid content in guinea pig skin irradiated by chronic ultraviolet A and B
- Journal of Oceanology and Limnology Vol. 22, Issue 4, Pages: 440-442(2004)
- Affiliations：
  
  Affiliated Hospital of Medical College Qingdao University
- Author bio：
- Funds：
- DOI：10.1007/BF02843643
  CLC：
- Published：2004
- Accepted：
Scan QR Code
Guoying, Y., Pengli, C., Kun, G. et al. Effects of polypeptide fromChlamys farreri on amino acid content in guinea pig skin irradiated by chronic ultraviolet A and B., Chin. J. Ocean. Limnol. 22, 440–442 (2004). https://doi.org/10.1007/BF02843643
DOI：

Guoying, Y., Pengli, C., Kun, G. et al. Effects of polypeptide fromChlamys farreri on amino acid content in guinea pig skin irradiated by chronic ultraviolet A and B., Chin. J. Ocean. Limnol. 22, 440–442 (2004). https://doi.org/10.1007/BF02843643 DOI：

摘要

Abstract

We examined the effects of polypeptide fromChlamys farreri (PCF) on the amount of hydroxyproline in guinea pig skin irradiated by chronic ultraviolet A (UVA) and ultraviolet B (UVB) radiation. PCF was applied locally before repeated exposure of guinea pig to UVA and UVB. The contents of hydroxyproline and other amino acids in guinea pig skin were determined by automatic amino acid analyzer. Our results showed that: (1) long-time UVA and UVB radiation can reduce dramatically the amounts of hydroxyproline

aspartic acid

threonine

glycine

phenylalanine and lysine in guinea pig skin in comparison with the control group (P<0.05); (2) Compared with model group

pre-treatment with 5% and 20% PCF prior to UVA and UVB radiation can inhibit the decline of amino acids content in guinea pig skin in a dose-dependent manner (P<0.05). As the decrease of hydroxyproline

glycine and lysine contents in the skin directly reflexes type I collagen degeneration

our results indicated that the chronic application of PCF can protect skin type I collagen against UV radiation

and thus protect skin from photoaging.

关键词

Keywords

references

Bissett, D. L., D. P. Hannon, and T. V. Orr, 1987. An animal model of solar-aged skin: histological, physical, and visible changes in UV irradiated hairless mouse skin.Photochem Photobiol. 46: 367–378.

Bissett, D. L., R. Chatterjee and D. P. Hannon, 1990. Photoprotective effect of topical anti-inflammatory agents against ultraviolet radiation-induced chronic skin damage in the hairless mouse.Photodermatol. Photoimmunol. Photomed. 7: 153–158.

Differy, B. D., 1987. Analysis of the risk of skin cancer from sunlight and solaria in subjects living in Northern Europe.Photodermatology 4: 118–126.

Eriko, S., F. Manabu, H. Minoru et al., 2002. CD19- dependent B lymphocyte signaling thresholds influence skin fibrosis and autoimmunity in the tight-skin mouse.J. Clin. Invest. 11: 1453–1462.

Halliday, G. M., B. O. Robertson and R. C. Barnetson, 2000. Topical retinoic acid enhances, and a dark tan protects, from subedemal solar-simulated photocarcinogenesis.J. Invest. Dermatol. 114: 923–927.

Masataka, S., T. Yoshitaka, K. Naomichi et al., 2001. Complete primary structure of rainbow trout type I collagen consisting of α1 (I) α2 (I) α3 (I) heterotrimers.Eur. J. Biochem. 268: 2817–2827.

Prockop, D. J., K. I. Kivirikko, 1995. Collagens: molecular biology, diseases, and potentials for therapy.Annu. Rev. Biochem. 64: 403–34.

Tornaletti, S. and G. P. Pfeifer, 1996. UV damage and repair mechanisms in mammalian cells.Bioessay 18: 221–232.

Uitto, J., 1979. Collagen polymorphism. Isolation and partial characterization of α1 (I) trimer molecules in normal human skin.Arch. Biochem. Biophys. 192: 371–379.

Urbach, F., 1989. Potential effects of altered solar ultraviolet radiation on human skin cancer.Protochem. Photobiol. 50: 507–513.

Wang, C. B., M. O. He, S. Z. Qin et al., 1998. Antioxidative effect of polypeptide fromChlamys farreri in vitro.Chinese Journal of Marine Drugs 3: 15–17.

Wang, C. B., R. Y. Yao, Z. T. Liu et al., 2002. Protective effects of polypeptide fromChlamys farreri on hairless mice damaged by ultraviolet A.Acta Pharmacol. Sin. 9: 813–818.

Yao, R. Y. and C. B. Wang, 2002. Protective effect of polypeptide fromChlamys farreri on HeLa cells damaged by ultraviolet A.Acta Pharmacol. Sin. 11: 1018–1022.

Views

Downloads

CSCD

Alert me when the article has been cited

Submit

Tools

Publicity Resources

Protective effect of topically applied polypeptide fromChlamys farreri against ultraviolet radiation-induced chronic skin damage in guinea pig

The polypeptide inChlamys farreri can protect human dermal fibroblasts from ultraviolet B damage

Research on Unsteady Characteristics ofUnderwater Supersonic Gas Jet

Effects of Rake Measurements on Turbine Efficiency

Parametric Model of Lubricant Particle Trajectory inAnnulus Inter-Spools

Related Author

Chi Mingliang

Cao Pengli

Yu Guoying

Zhu Li

Wang Yuejun

Wang Chunbo

Zhang Yujiang

Zhan Songmei

Related Institution

Medical College Qingdao University

Medical College Qingdao University Qingdao

Yellow Sea Fishery Research Institute Qingdao

Address：Editorial Office of JOL, 88 Haijun Rd. Qingdao, 266000, China
Tel：+86-532-82898754 Email：jol@qdio.ac.cn
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备09064830号-19 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰