Qi-wei, Q., Zao-he, W. & Jin-pei, P. Disease resistance and humoral immunomodulatory effects of vitamin C on grouper,Epinephelus awoara, ., Chin. J. Ocean. Limnol. 18, 247–252 (2000). https://doi.org/10.1007/BF02842671
DOI:
Qi-wei, Q., Zao-he, W. & Jin-pei, P. Disease resistance and humoral immunomodulatory effects of vitamin C on grouper,Epinephelus awoara, ., Chin. J. Ocean. Limnol. 18, 247–252 (2000). https://doi.org/10.1007/BF02842671DOI:
Disease resistance and humoral immunomodulatory effects of vitamin C on grouper,Epinephelus awoara
摘要
Abstract
The disease resistance and humoral immunomodulatory effects of vitamin C administered orally to grouper
Epinephelus awoara maintained on a frozen fish diet supplemented with vitamin C at 500
1000
1500 and 2000 mg/kg were investigated. After 20 weeks
the growth rates of the groups with high level of vitamin C apparently increased. The untreated fish had symptoms of vitamin C deficiency. The endogenous liver tissue vitamin C levels were found to reflect well the dietary treatments. After intraperitoneal injection or bath challenge with a virulent strain ofVibrio vulnificus
fish fed with high level vitamin C showed significantly higher survival rate compared with the normal control group. Vaccination with formalin inactivatedV. vulnificus significantly enhanced the specific antibody production in fish treated with vitamin C
and completely protected from strong bacterial challenge the groups fed on fish with vitamin C 1500 and 2000 mg/kg diet.
关键词
Keywords
references
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