Integrated biomarker response to assess toxic impacts of iron and manganese on deep-sea mussel <italic style="font-style: italic">Gigantidas</italic> <italic style="font-style: italic">platifrons</italic> under a deep-sea mining activity scenario

Li ZHOU; Mengna LI; Zhaoshan ZHONG; Minxiao WANG; Hao CHEN; Chao LIAN; Hao WANG; Huan ZHANG; Lei CAO; Chaolun LI

doi:10.1007/s00343-023-3048-y

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Integrated biomarker response to assess toxic impacts of iron and manganese on deep-sea mussel Gigantidas platifrons under a deep-sea mining activity scenario

Ecology | Updated：2024-10-11

- Integrated biomarker response to assess toxic impacts of iron and manganese on deep-sea mussel Gigantidas platifrons under a deep-sea mining activity scenario
- Integrated biomarker response to assess toxic impacts of iron and manganese on deep-sea mussel Gigantidas platifrons under a deep-sea mining activity scenario
- 海洋湖沼学报(英文) 2024年42卷第2期页码：522-532
- Affiliations：
  
  1.Center of Deep Sea Research, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China
  2.Laoshan Laboratory, Qingdao 266237, China
  3.South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China
  4.CAS Key Laboratory of Marine Ecology and Environmental Sciences, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China
  5.University of Chinese Academy of Sciences, Beijing 100049, China
- Author bio：
  
  lcl@qdio.ac.cn
- Funds：
  
  the Marine S&T Fund of Shandong Province for Qingdao Marine Science and Technology Center(2022QNLM030004-1);the National Natural Science Foundation of China(42276153;42030407);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB42020401);the Key Research Program of Frontier Sciences, CAS(ZDBS-LY-DQC032);the National Key R&D program of China(2022YFC2804003)
- DOI：10.1007/s00343-023-3048-y
  中图分类号：
- 收稿：2023-03-23，
  
  网络首发：2023-04-13，
  
  纸质出版：2024-03-01
- Accepted：
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Integrated biomarker response to assess toxic impacts of iron and manganese on deep-sea mussel Gigantidas platifrons under a deep-sea mining activity scenario[J]. 海洋湖沼学报(英文), 2024,42(2):522-532.

ZHOU Li,LI Mengna,ZHONG Zhaoshan,et al.Integrated biomarker response to assess toxic impacts of iron and manganese on deep-sea mussel Gigantidasplatifrons under a deep-sea mining activity scenario[J].Journal of Oceanology and Limnology,2024,42(02):522-532.
Integrated biomarker response to assess toxic impacts of iron and manganese on deep-sea mussel Gigantidas platifrons under a deep-sea mining activity scenario[J]. 海洋湖沼学报(英文), 2024,42(2):522-532. DOI： 10.1007/s00343-023-3048-y.

ZHOU Li,LI Mengna,ZHONG Zhaoshan,et al.Integrated biomarker response to assess toxic impacts of iron and manganese on deep-sea mussel Gigantidasplatifrons under a deep-sea mining activity scenario[J].Journal of Oceanology and Limnology,2024,42(02):522-532. DOI： 10.1007/s00343-023-3048-y.

摘要

Abstract

Deep-sea mining activities can potentially release metals

which pose a toxicological threat to deep-sea ecosystems. Nevertheless

due to the remoteness and inaccessibility of the deep-sea biosphere

there is insufficient knowledge about the impact of metal exposure on its inhabitants. In this study

deep-sea mussel

Gigantidas

platifrons

a commonly used deep-sea toxicology model organism

was exposed to manganese (100

1 000 µg/L) or iron (500

5 000 µg/L) for 7 d

respectively. Manganese and iron were chosen for their high levels of occurrence within deep-sea deposits. Metal accumulation and a battery of biochemical biomarkers related to antioxidative stress in superoxide dismutase (SOD)

catalase (CAT)

malondialdehyde (MDA); immune function in alkaline phosphatase (AKP)

acid phosphatase (ACP); and energy metabolism in pyruvate kinase (PK) and hexokinase (HK) were assessed in mussel gills. Results showed that deep-sea mussel

platifrons

exhibited a high capacity to accumulate Mn/Fe. In addition

most tested biochemical parameters were altered by metal exposure

demonstrating that metals could induce oxidative stress

suppress the immune system

and affect energy metabolism of deep-sea mussels. The integrated biomarker response (IBR) approach indicated that the exposure to Mn/Fe had a negative impact on deep-sea mussels

and Mn demonstrated a more harmful impact on deep-sea mussels than Fe. Additionally

SOD and CAT biomarkers had the greatest impact on IBR values in Mn treatments

while ACP and HK were most influential for the low- and high-dose Fe groups

respectively. This study represents the first application of the IBR approach to evaluate the toxicity of metals on deep-sea fauna and serves as a crucial framework for risk assessment of deep-sea mining-associated metal exposure.

关键词

Keywords

references

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Integrated biomarker response to assess toxic impacts of iron and manganese on deep-sea mussel Gigantidas platifrons under a deep-sea mining activity scenario

Integrated biomarker response to assess toxic impacts of iron and manganese on deep-sea mussel Gigantidas platifrons under a deep-sea mining activity scenario

DOI：10.1007/s00343-023-3048-y

摘要

Abstract

关键词

Keywords

references