Phlorizin alleviates deltamethrin-induced oxidative stress in brine shrimp <italic style="font-style: italic">Artemia</italic>

Dandan MA; Qingli ZHOU; Liying SUI; Qingbin GUO; Huanhuan LIU; Honghe LIANG; Zhenjing LI; Zhongna SANG

doi:10.1007/s00343-023-2387-z

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Phlorizin alleviates deltamethrin-induced oxidative stress in brine shrimp Artemia

Ecology | Updated：2024-10-15

- Phlorizin alleviates deltamethrin-induced oxidative stress in brine shrimp Artemia
- Phlorizin alleviates deltamethrin-induced oxidative stress in brine shrimp Artemia
- 海洋湖沼学报(英文) 2024年42卷第1期页码：163-173
- Affiliations：
  
  1.School of Food Science and Engineering, Tianjin University of Science and Technology, Tianjin 300457, China
  2.Asian Regional Artemia Reference Center, Key Laboratory of Marine Resource Chemistry and Food Technology (TUST), Ministry of Education, Tianjin University of Science and Technology, Tianjin 300457, China
  3.Subtropical Crops Research Institute of Guangxi Zhuang Autonomous Region, Nanning 530001, China
  4.Department of Nutrition and Food Hygiene, School of Public Health, Tianjin Medical University, Tianjin 300070, China
- Author bio：
  
  3055906252@qq.com
  sangzhongna@tm.edu.cn
- Funds：
  
  the Key Laboratory of Marine Resource Chemistry and Food Technology (TUST), the Ministry of Education(EMTUST-21-08);the Guilin Science and Technology Project(20210225-4)
- DOI：10.1007/s00343-023-2387-z
  中图分类号：
- 收稿：2022-12-14，
  
  录用：2023-02-09，
  
  网络首发：2023-03-15，
  
  纸质出版：2024-01-03
- Accepted：
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Phlorizin alleviates deltamethrin-induced oxidative stress in brine shrimp Artemia[J]. 海洋湖沼学报(英文), 2024,42(1):163-173.

MA Dandan,ZHOU Qingli,SUI Liying,et al.Research Paper Phlorizin alleviates deltamethrin-induced oxidative stress in brine shrimp Artemia[J].Journal of Oceanology and Limnology,2024,42(01):163-173.
Phlorizin alleviates deltamethrin-induced oxidative stress in brine shrimp Artemia[J]. 海洋湖沼学报(英文), 2024,42(1):163-173. DOI： 10.1007/s00343-023-2387-z.

MA Dandan,ZHOU Qingli,SUI Liying,et al.Research Paper Phlorizin alleviates deltamethrin-induced oxidative stress in brine shrimp Artemia[J].Journal of Oceanology and Limnology,2024,42(01):163-173. DOI： 10.1007/s00343-023-2387-z.

摘要

Abstract

Deltamethrin (DEL)

a commonly used pyrethroid pesticide

results in higher reactive oxygen species (ROS) levels in aquatic animals

which consequently unbalance the redox state. Phlorizin (PHL) is a flavonoid and a natural product promising to prevent or reduce pesticide-induce

d oxidative stress.

Artemia

is a micro-crustacean widely used in marine hatcheries and an experimental aquatic organism for environmental toxicology research. This research aimed to evaluate the toxicity of DEL on

Artemia

and the antioxidative effect of PHL against the toxicity. Results show that 0.08-mg/mL PHL exerted its antioxidative effects on hatching percentage of the cysts in 24-h incubation and on body length and survival rate of

Artemia

in 12-d culture. After 12-d culture

12-

24-

and 36-h DEL exposure showed significant drops in SOD

CAT

and GSH-Px enzyme activities

and significant increases in ROS and malondialdehyde (MDA) levels in

Artemia

(

0.05). On the contrary

0.08-mg/mL PHL application improved the enzyme activities and decreased the ROS and MDA levels (

0.05). Moreover

0.08-mg/mL PHL significantly increased mRNA expression levels of

Zn SOD

CAT

GST

NQO1

and

Nrf2

and decreased mRNA expression level of

Keap1

in the DEL-exposed

Artemia

(

0.05). Therefore

DEL is toxic to

Artemia

while PHL alleviates DEL-induced oxidative damage by possibly regulating the Nrf2 signaling pathway. This study provided a theoretical basis for PHL to reduce pesticide-induced toxicity in aquatic animals.

关键词

Keywords

references

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Phlorizin alleviates deltamethrin-induced oxidative stress in brine shrimp Artemia

Phlorizin alleviates deltamethrin-induced oxidative stress in brine shrimp Artemia

DOI：10.1007/s00343-023-2387-z

摘要

Abstract

关键词

Keywords

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