Roles of interleukins in antibacterial immune defense of the brood pouch in the lined seahorse <italic style="font-style: italic">Hippocampus erectus</italic>

Han JIANG; Chunyan LI; Bo ZHANG; Yongli WU; Qiang LIN

doi:10.1007/s00343-021-0310-z

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Roles of interleukins in antibacterial immune defense of the brood pouch in the lined seahorse Hippocampus erectus

Biology | Updated：2023-04-27

- Roles of interleukins in antibacterial immune defense of the brood pouch in the lined seahorse Hippocampus erectus
- Roles of interleukins in antibacterial immune defense of the brood pouch in the lined seahorse Hippocampus erectus
- 海洋湖沼学报（英文） 2022年40卷第1期页码：235-244
- Affiliations：
  
  1.CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China
  2.Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China
  3.University of Chinese Academy of Sciences, Beijing 100049, China
- Author bio：
  
  Chunyan LI, E-mail: cyli@scsio.ac.cn
  Qiang LIN, E-mail: linqiang@scsio.ac.cn
- Funds：
  
  the National Science & Technology Fundamental Resources Investigation Program of China(2018FY100106);the National Natural Science Foundation of China(41825013);the National Natural Science Foundation of China(41806189);the Key Special Project for Introduced Talents Team of Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)(GML2019ZD0407);the K. C. Wong Education Foundation, and the Guangdong Special Support Program of Leading Scientific and Technological Innovation(2017TX04N442);© Chinese Society for Oceanology and Limnology, Science Press and Springer-Verlag GmbH Germany, part of Springer Nature 2022
- DOI：10.1007/s00343-021-0310-z
  中图分类号：
- 收稿：2020-08-19，
  
  录用：2020-9-25，
  
  网络首发：2021-01-19，
  
  纸质出版：2022-01
- Accepted：
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Roles of interleukins in antibacterial immune defense of the brood pouch in the lined seahorse Hippocampus erectus[J]. 海洋湖沼学报（英文）, 2022,40(1):235-244.

Han JIANG, Chunyan LI, Bo ZHANG, et al. Roles of interleukins in antibacterial immune defense of the brood pouch in the lined seahorse Hippocampus erectus[J]. Journal of Oceanology and Limnology, 2022, 40(1): 235-244.
Roles of interleukins in antibacterial immune defense of the brood pouch in the lined seahorse Hippocampus erectus[J]. 海洋湖沼学报（英文）, 2022,40(1):235-244. DOI： 10.1007/s00343-021-0310-z.

Han JIANG, Chunyan LI, Bo ZHANG, et al. Roles of interleukins in antibacterial immune defense of the brood pouch in the lined seahorse Hippocampus erectus[J]. Journal of Oceanology and Limnology, 2022, 40(1): 235-244. DOI： 10.1007/s00343-021-0310-z.

摘要

Abstract

Seahorse embryos are brooded in the enclosed nutrient-rich environment of the male brood pouch

which may be prone to bacterial infection. The immune responses of interleukin (IL) genes in the brood pouch have not been well studied. We identified 13 interleukins in the lined seahorse

Hippocampus erectus

. Tissue-specific expression analysis revealed increased mRNA expression levels of

il-1β

il-18

and

il-8

in the brood pouch. When challenged with lipopolysaccharide or

Vibrio parahaemolyticus

il-1β

and

il-18

were active as part of the acute and chronic inflammatory responses

respectively. Importantly

il-8

may be involved in powerful antibacterial immune responses and may be induced by

il-1β

and

il-18

via a process involving the nuclear factor-κB signaling pathway. These results suggest that

il-1β

il-18

and

il-8

may play key roles in the antibacterial immune defense of the brood pouch in male seahorses.

关键词

Keywords

references

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Roles of interleukins in antibacterial immune defense of the brood pouch in the lined seahorse Hippocampus erectus

Roles of interleukins in antibacterial immune defense of the brood pouch in the lined seahorse Hippocampus erectus

DOI：10.1007/s00343-021-0310-z

摘要

Abstract

关键词

Keywords

references