Prevalence and risk assessment of antibiotics in riverine estuarine waters of Larut and Sangga Besar River, Perak

Kyleyoung LOW; Layching CHAI; Choonweng LEE; Gan ZHANG; Ruijie ZHANG; Vaezzadeh VAHAB; Chuiwei BONG

doi:10.1007/s00343-020-9246-y

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Prevalence and risk assessment of antibiotics in riverine estuarine waters of Larut and Sangga Besar River, Perak

Chemistry | Updated：2023-05-20

- Prevalence and risk assessment of antibiotics in riverine estuarine waters of Larut and Sangga Besar River, Perak
- Prevalence and risk assessment of antibiotics in riverine estuarine waters of Larut and Sangga Besar River, Perak
- 海洋湖沼学报（英文） 2021年39卷第1期页码：122-134
- Affiliations：
  
  1.Institute of Ocean and Earth Sciences (IOES), University of Malaya, Kuala Lumpur 50603, Malaysia
  2.Institute of Graduate Studies, University of Malaya, Kuala Lumpur 50603, Malaysia
  3.Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia
  4.Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China
  5.School of Marine Sciences, Guangxi University, Nanning 530004, China
- Author bio：
  
  Chuiwei BONG, cwbong@um.edu.my
- Funds：
  
  the Ministry of Higher Education of Malaysia(IOES-2014D);the Ministry of Higher Education of Malaysia(FP048-2013A);the Ministry of Higher Education of Malaysia(SF022-2013);the University Malaya(RU009D-2015);the University Malaya(PG309-2016A);© Chinese Society for Oceanology and Limnology, Science Press and Springer-Verlag GmbH Germany, part of Springer Nature 2021
- DOI：10.1007/s00343-020-9246-y
  中图分类号：
- 收稿：2019-09-24，
  
  录用：2019-12-18，
  
  网络首发：2020-03-11，
  
  纸质出版：2021-01
- Accepted：
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Prevalence and risk assessment of antibiotics in riverine estuarine waters of Larut and Sangga Besar River, Perak[J]. 海洋湖沼学报（英文）, 2021,39(1):122-134.

Kyleyoung LOW, Layching CHAI, Choonweng LEE, et al. Prevalence and risk assessment of antibiotics in riverine estuarine waters of Larut and Sangga Besar River, Perak[J]. Journal of Oceanology and Limnology, 2021, 39(1): 122-134.
Prevalence and risk assessment of antibiotics in riverine estuarine waters of Larut and Sangga Besar River, Perak[J]. 海洋湖沼学报（英文）, 2021,39(1):122-134. DOI： 10.1007/s00343-020-9246-y.

Kyleyoung LOW, Layching CHAI, Choonweng LEE, et al. Prevalence and risk assessment of antibiotics in riverine estuarine waters of Larut and Sangga Besar River, Perak[J]. Journal of Oceanology and Limnology, 2021, 39(1): 122-134. DOI： 10.1007/s00343-020-9246-y.

摘要

Abstract

Antibiotics released into the environment through anthropogenic activities exert selective pressure

driving bacteria towards increasing antimicrobial resistance. The prevalence of antibiotics and the ecological risks posed in the riverine estuarine of Larut River and Sangga Besar River

which included wastewater effluents from hospital

zoo

and poultry slaughterhouse sources were investigated. Solid phase extraction (SPE) followed by high-performance liquid chromatography tandem mass chromatography (HPLC-MS/MS) were used to extract and quantify the antibiotic residues from 22 antibiotics belonging to six major antibiotic classes (sulfonamide

macrolide

fluoroquinolone

phenicol

trimethoprim

and tetracycline). Sixteen antibiotic residues were detected with concentrations ranging from limit of detection (LOD) to 1 262.3 ng/L. Fluoroquinolones and macrolides were the most frequently detected compounds. Erythromycin

clarithromycin

and ofloxacin detected in hospital and zoo effluents posed a high risk to algae while tetracycline had low to medium ecological risks toward all the relevant organisms from aquatic environments (algae

invertebrate

Daphnia magna

and fish).

关键词

Keywords

references

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