Antioxidant bisabolane-type sesquiterpenoids from algalderived fungus <italic style="font-style: italic">Aspergillus sydowii</italic> EN-434

Xueyi HU; Xiaoming LI; Linghong MENG; Bingui WANG

doi:10.1007/s00343-020-0049-y

Your Location：

Home >

Browse articles >

Antioxidant bisabolane-type sesquiterpenoids from algalderived fungus Aspergillus sydowii EN-434

Chemistry | Updated：2023-04-27

- Antioxidant bisabolane-type sesquiterpenoids from algalderived fungus Aspergillus sydowii EN-434
- Antioxidant bisabolane-type sesquiterpenoids from algalderived fungus Aspergillus sydowii EN-434
- 海洋湖沼学报（英文） 2020年38卷第5期页码：1532-1536
- Affiliations：
  
  1.Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, and Laboratory of Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao 266071, China
  2.College of Earth Science, University of Chinese Academy of Sciences, Beijing 100049, China
  3.Center for Ocean Mega-Science, Chinese Academy of Sciences, Qingdao 266071, China
- Author bio：
  
  MENG Linghong, menglh@qdio.ac.cn
  WANG Bingui, wangbg@qdio.ac.cn
- Funds：
  
  National Natural Science Foundation of China(31330009);National Natural Science Foundation of China(31600267);© Chinese Society for Oceanology and Limnology, Science Press and Springer-Verlag GmbH Germany, part of Springer Nature 2020
- DOI：10.1007/s00343-020-0049-y
  中图分类号：
- 收稿：2020-01-23，
  
  录用：2020-4-3，
  
  网络首发：2020-05-05，
  
  纸质出版：2020-09
- Accepted：
Scan QR Code
Antioxidant bisabolane-type sesquiterpenoids from algalderived fungus Aspergillus sydowii EN-434[J]. 海洋湖沼学报（英文）, 2020,38(5):1532-1536.

Xueyi HU, Xiaoming LI, Linghong MENG, et al. Antioxidant bisabolane-type sesquiterpenoids from algalderived fungus Aspergillus sydowii EN-434[J]. Journal of Oceanology and Limnology, 2020, 38(5): 1532-1536.
Antioxidant bisabolane-type sesquiterpenoids from algalderived fungus Aspergillus sydowii EN-434[J]. 海洋湖沼学报（英文）, 2020,38(5):1532-1536. DOI： 10.1007/s00343-020-0049-y.

Xueyi HU, Xiaoming LI, Linghong MENG, et al. Antioxidant bisabolane-type sesquiterpenoids from algalderived fungus Aspergillus sydowii EN-434[J]. Journal of Oceanology and Limnology, 2020, 38(5): 1532-1536. DOI： 10.1007/s00343-020-0049-y.

摘要

Abstract

A new aromatic bisabolene-type sesquiterpenoid (7

)-8-hydroxysydowic acid (

)

together with a pair of new bisabolene derivative (±)-(7

)-10-hydroxysydowic acid (

)

as well as two known analogues hydroxysydonic acid (

) and sydowic acid (

) were isolated and identified from the endophytic fungal strain

Aspergillus sydowii

EN-434 that was obtained from the marine red alga

Symphyocladia latiuscula

. Their structures were elucidated by nuclear magnetic resonance (NMR)

high resolution electrospray ionization mass spectroscopy (HRESIMS)

and quantum chemical electronic circular dichroism (ECD) calculations as well as comparison of the data with literature reports. Compound

exhibited potent DPPH free radical scavenging activity with IC

value of 113.5 μmol/L.

关键词

Keywords

references

N Barzkar , S T Jahromi , H B Poorsaheli , F Vianello . Metabolites from marine microorganisms, micro, and macroalgae:immense scope for pharmacology . Mar.Drugs , 2019 . 17 ( 8 ): 464 DOI: 10.3390/md17080464 http://doi.org/10.3390/md17080464 .

J W Blunt , B R Copp , R A Keyzers , M H G Munro , M R Prinsep . Marine natural products . Nat. Prod. Rep. , 2015 . 32 ( 2 ): 116 - 211 . DOI: 10.1039/C4NP00144C http://doi.org/10.1039/C4NP00144C .

K H Cho , J H Sohn , H Oh . Isolation and structure determination of a new diketopiperazine dimer from marine-derived fungus Aspergillus sp. SF-5280 . Nat.Prod. Res. , 2018 . 32 ( 2 ): 214 - 221 . DOI: 10.1080/14786419.2017.1346642 http://doi.org/10.1080/14786419.2017.1346642 .

M J Frisch , G W Trucks , H B Schlegel , 等 . Gaussian 09, Revision D.01 , : Wallingford, CT Gaussian, Inc , 2013 .

T Hamasaki , K Nagayama , Y Hatsuda . Two new metabolites, sydonic acid and hydroxysydonic acid, from Aspergillus sydowi . Agric. Biol. Chem. , 1978 . 42 ( 1 ): 37 - 40 . DOI: 10.1271/bbb1961.42.37 http://doi.org/10.1271/bbb1961.42.37 .

T Hamasaki , Y Sato , Y Hatsuda , M Tanabe , L W Cary . Sydowic acid, a new metabolite from Aspergillus sydowi . Tetrahedron Lett. , 1975 . 16 ( 9 ): 659 - 660 . DOI: 10.1016/S0040-4039(00)71947-2 http://doi.org/10.1016/S0040-4039(00)71947-2 DOI: 10.1016/S0040-4039(00)71947-2 http://doi.org/10.1016/S0040-4039(00)71947-2 .

W T Li , D Luo , J N Huang , L L Wang , F G Zhang , T Xi , J M Liao , Y Y Lu . Antibacterial constituents from Antarctic fungus, Aspergillus sydowii SP-1 . Nat. Prod. Res. , 2018 . 32 ( 6 ): 662 - 667 . DOI: 10.1080/14786419.2017.1335730 http://doi.org/10.1080/14786419.2017.1335730 .

S Liu , H B Wang , M Z Su , G J Hwang , J K Hong , J H Jung . New metabolites from the sponge-derived fungus Aspergillus sydowii J05B-7F-4 . Nat. Prod. Res. , 2017 . 31 ( 14 ): 1 682 - 1 686 . DOI: 10.1080/14786419.2017.1289205 http://doi.org/10.1080/14786419.2017.1289205 .

X R Liu , F H Song , L Ma , C X Chen , X Xiao , B Ren , X T Liu , H Q Dai , A M Piggott , Y Av-Gay , L X Zhang , R J Capon . Sydowiols A-C: Mycobacterium tuberculosis protein tyrosine phosphatase inhibitors from an East China Sea marine-derived fungus, Aspergillus sydowii . Tetrahedron Lett. , 2013 . 54 ( 45 ): 6 081 - 6 083 . DOI: 10.1016/j.tetlet.2013.08.137 http://doi.org/10.1016/j.tetlet.2013.08.137 .

C Schinke , T Martins , S C N Queiroz , I S Melo , F G R Reyes . Antibacterial compounds from marine bacteria, 2010-2015 . J. Nat. Prod. , 2017 . 80 ( 4 ): 1 215 - 1 228 . DOI: 10.1021/acs.jnatprod.6b00235 http://doi.org/10.1021/acs.jnatprod.6b00235 .

D Tasdemir . Marine fungi in the spotlight:opportunities and challenges for marine fungal natural product discovery and biotechnology . Fungal Biol. Biotechnol. , 2017 . 4 ( 1 ): 5 DOI: 10.1186/s40694-017-0034-1 http://doi.org/10.1186/s40694-017-0034-1 .

F Teuscher , W H Lin , V Wray , R Edrada , K Padmakumar , P Proksch , R Ebel . Two new cyclopentanoids from the endophytic fungus Aspergillus sydowii associated with the marine alga Acanthophora spicifera . Nat. Prod.Comm. , 2006 . 1 ( 11 ): 927 - 933 . DOI: 10.1177/193457 8X0600101103 http://doi.org/10.1177/193457 8X0600101103 .

K Trisuwan , V Rukachaisirikul , M Kaewpet , S Phongpaichit , N Hutadilok-Towatana , S Preedanon , J Sakayaroj . Sesquiterpene and xanthone derivatives from the sea fanderived fungus Aspergillus sydowii PSU-F154 . J. Nat. Prod. , 2011 . 74 ( 7 ): 1 663 - 1 667 . DOI: 10.1021/np200374j http://doi.org/10.1021/np200374j .

S Wang , X M Li , F Teuscher , D L Li , A Diesel , R Ebel , P Proksch , B G Wang . Chaetopyranin, a benzaldehyde derivative, and other related metabolites from Chaetomium globosum , an endophytic fungus derived from the marine red alga Polysiphonia urceolata . J. Nat. Prod. , 2006 . 69 ( 11 ): 1 622 - 1 625 . DOI: 10.1021/np060248n http://doi.org/10.1021/np060248n .

W L Wang , Z Y Lu , H W Tao , T J Zhu , Y C Fang , Q Q Gu , W M Zhu . Isoechinulin-type alkaloids, Variecolorins A-L, from halotolerant Aspergillus variecolor . J. Nat. Prod. , 2007 . 70 ( 10 ): 1 558 - 1 564 . DOI: 10.1021/np070208z http://doi.org/10.1021/np070208z .

Y N Wang , Y H Mou , Y Dong , Y Wu , B Y Liu , J Bai , D J Yan , L Zhang , D Q Feng , Y H Pei , Y C Hu . Diphenyl ethers from a marine-derived Aspergillus sydowii . Mar.Drugs , 2018 . 16 ( 11 ): 451 DOI: 10.3390/md16110451 http://doi.org/10.3390/md16110451 .

X L Xu , S J Zhao , L Y Yin , Y Yu , Z K Chen , H H Shen , L Zhou . A new sydonic acid derivative from a marine derivedfungus Aspergillus sydowii . Chem. Nat. Compd. , 2017 . 53 ( 6 ): 1 056 - 1 058 . DOI: 10.1007/s10600-017-2200-3 http://doi.org/10.1007/s10600-017-2200-3 .

浏览量

Downloads

CSCD

文章被引用时，请邮件提醒。

Submit

工具集

关联资源

Response surface optimization of preparation parameters and evaluation of the antioxidant and antihypertensive activities of Spirulina protein hydrolysates

A novel enzyme-assisted one-pot method for the extraction of fucoidan and alginate oligosaccharides from Lessonia trabeculata and their bioactivities

Synthesis, characterization, and antioxidant activity of carboxymethyl chitosan derivatives containing sulfonium salt

Antioxidative and antimicrobial activities of intertidal seaweeds and possible effects of abiotic factors on these bioactivities

含缺陷轮盘失效概率分析流程与数值模拟

Antioxidant bisabolane-type sesquiterpenoids from algalderived fungus Aspergillus sydowii EN-434

Antioxidant bisabolane-type sesquiterpenoids from algalderived fungus Aspergillus sydowii EN-434

DOI：10.1007/s00343-020-0049-y

摘要

Abstract

关键词

Keywords

references