Phlorizin alleviates deltamethrin-induced oxidative stress in brine shrimp <italic style="font-style: italic">Artemia</italic>

Dandan MA; Qingli ZHOU; Liying SUI; Qingbin GUO; Huanhuan LIU; Honghe LIANG; Zhenjing LI; Zhongna SANG

doi:10.1007/s00343-023-2387-z

Your Location：

Home >

Browse articles >

Phlorizin alleviates deltamethrin-induced oxidative stress in brine shrimp Artemia

Ecology | Updated：2024-10-15

- Phlorizin alleviates deltamethrin-induced oxidative stress in brine shrimp Artemia
- Journal of Oceanology and Limnology Vol. 42, Issue 1, Pages: 163-173(2024)
- Affiliations：
  
  1.School of Food Science and Engineering, Tianjin University of Science and Technology, Tianjin 300457, China
  2.Asian Regional Artemia Reference Center, Key Laboratory of Marine Resource Chemistry and Food Technology (TUST), Ministry of Education, Tianjin University of Science and Technology, Tianjin 300457, China
  3.Subtropical Crops Research Institute of Guangxi Zhuang Autonomous Region, Nanning 530001, China
  4.Department of Nutrition and Food Hygiene, School of Public Health, Tianjin Medical University, Tianjin 300070, China
- Author bio：
  
  3055906252@qq.com
  sangzhongna@tm.edu.cn
- Funds：
- DOI：10.1007/s00343-023-2387-z
  CLC：
- Received：14 December 2022，
  
  Accepted：09 February 2023，
  
  Online First：15 March 2023，
  
  Published：03 January 2024
- Accepted：
Scan QR Code
MA Dandan,ZHOU Qingli,SUI Liying,et al.Research Paper Phlorizin alleviates deltamethrin-induced oxidative stress in brine shrimp Artemia[J].Journal of Oceanology and Limnology,2024,42(01):163-173.
DOI：

MA Dandan,ZHOU Qingli,SUI Liying,et al.Research Paper Phlorizin alleviates deltamethrin-induced oxidative stress in brine shrimp Artemia[J].Journal of Oceanology and Limnology,2024,42(01):163-173. DOI： 10.1007/s00343-023-2387-z.

摘要

Abstract

Deltamethrin (DEL)

a commonly used pyrethroid pesticide

results in higher reactive oxygen species (ROS) levels in aquatic animals

which consequently unbalance the redox state. Phlorizin (PHL) is a flavonoid and a natural product promising to prevent or reduce pesticide-induce

d oxidative stress.

Artemia

is a micro-crustacean widely used in marine hatcheries and an experimental aquatic organism for environmental toxicology research. This research aimed to evaluate the toxicity of DEL on

Artemia

and the antioxidative effect of PHL against the toxicity. Results show that 0.08-mg/mL PHL exerted its antioxidative effects on hatching percentage of the cysts in 24-h incubation and on body length and survival rate of

Artemia

in 12-d culture. After 12-d culture

12-

24-

and 36-h DEL exposure showed significant drops in SOD

CAT

and GSH-Px enzyme activities

and significant increases in ROS and malondialdehyde (MDA) levels in

Artemia

(

0.05). On the contrary

0.08-mg/mL PHL application improved the enzyme activities and decreased the ROS and MDA levels (

0.05). Moreover

0.08-mg/mL PHL significantly increased mRNA expression levels of

Zn SOD

CAT

GST

NQO1

and

Nrf2

and decreased mRNA expression level of

Keap1

in the DEL-exposed

Artemia

(

0.05). Therefore

DEL is toxic to

Artemia

while PHL alleviates DEL-induced oxidative damage by possibly regulating the Nrf2 signaling pathway. This study provided a theoretical basis for PHL to reduce pesticide-induced toxicity in aquatic animals.

关键词

Keywords

references

Alishahi M , Tulaby Dezfuly Z T . 2019 . Comparative toxicities of five herbicides on nauplii of Artemia franciscana as an ecotoxicity bioindicator . Iranian Journal of Fisheries Sciences , 18 ( 4 ): 716 - 726 , https://doi.org/10.22092/IJFS.2019.118284 https://doi.org/10.22092/IJFS.2019.118284 .

Anguita-Ruiz A , Aguilera C M , Gil Á . 2020 . Genetics of lactose intolerance: an updated review and online interactive world maps of phenotype and genotype frequencies . Nutrients , 12 ( 9 ): 2689 , https://doi.org/10.3390/nu12092689 https://doi.org/10.3390/nu12092689 .

Arslan H , Altun S , Özdemir S . 2017 . Acute toxication of deltamethrin results in activation of iNOS, 8-OHdG and up-regulation of caspase 3, iNOS gene expression in common carp ( Cyprinus carpio L.) . Aquatic Toxicology , 187 : 90 - 99 , https://doi.org/10.1016/j.aquatox.2017.03.014 https://doi.org/10.1016/j.aquatox.2017.03.014 .

Awoyemi O M , Kumar N , Schmitt C et al . 2019 . Behavioral, molecular and physiological responses of embryo-larval zebrafish exposed to types I and II pyrethroids . Chemosphere , 219 : 526 - 537 , https://doi.org/10.1016/j.chemosphere.2018.12.026 https://doi.org/10.1016/j.chemosphere.2018.12.026 .

Bradford M . 1976 . A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein-dye-binding . Analyt. Biochem. , 72 : 248 . https://do 10.1016/0003-2697(76)90527-3 http://dx.doi.org/10.1016/0003-2697(76)90527-3

Chakraborty S , Bornhorst J , Nguyen T T et al . 2013 . Oxidative stress mechanisms underlying Parkinson's disease-associated neurodegeneration in C . elegans . International Journal of Molecular Sciences , 14 ( 11 ): 23103 - 23128 , https://doi.org/10.3390/ijms141123103 https://doi.org/10.3390/ijms141123103 .

Chen X M , Yang W Q , Wang X et al . 2022 . Effects of natural dihydrochalcones in sweet tea ( Lithocarpus polystachyus ) on diabetes: a systematical review and meta-analysis of animal studies . Food & Function , 13 ( 11 ): 5899 - 5913 , https://doi.org/10.1039/D2FO00245K https://doi.org/10.1039/D2FO00245K .

David-Silva A , Esteves J V , Morais M R P T et al . 2020 . Dual SGLT1/SGLT2 inhibitor phlorizin ameliorates non-alcoholic fatty liver disease and hepatic glucose production in type 2 diabetic mice . Diabetes, Metabolic Syndrome and Obesity , 13 : 739 - 751 , https://doi.org/10.2147/DMSO.S242282 https://doi.org/10.2147/DMSO.S242282 .

Dawood M A O , AbdEl-Kader M F , Moustafa E M et al . 2020 . Growth performance and hemato-immunological responses of Nile tilapia ( Oreochromis niloticus ) exposed to deltamethrin and fed immunobiotics . Environmental Science and Pollution Research , 27 ( 11 ): 11608 - 11617 , https://doi.org/10.1007/s11356-020-07775-8 https://doi.org/10.1007/s11356-020-07775-8 .

Ding R Q , Cao Z F , Wang Y H et al . 2017 . The implication of p66shc in oxidative stress induced by deltamethrin . Chemico-Biological Interactions , 278 : 162 - 169 , https://doi.org/10.1016/j.cbi.2017.10.005 https://doi.org/10.1016/j.cbi.2017.10.005 .

Ehrenkranz J R L , Lewis N G , Kahn C R et al . 2005 . Phlorizin: a review . Diabetes/Metabolism Research and Reviews , 21 ( 1 ): 31 - 38 , https://doi.org/10.1002/dmrr.532 https://doi.org/10.1002/dmrr.532 .

El-Hawary S S , Hammam W E , El-Tantawi M E M et al . 2021 . Apple leaves and their major secondary me tabolite phlorizin exhibit distinct neuroprotective activities: evidence from in vivo and in silico studies . Arabian Journal of Chemistry , 14 ( 6 ): 103188 , https://doi.org/10.1016/j.arabjc.2021.103188 https://doi.org/10.1016/j.arabjc.2021.103188 .

Elia A C , Giorda F , Pacini N et al . 2017 . Subacute toxicity effects of deltamethrin on oxidative stress markers in rainbow trout . Journal of Aquatic Animal Health , 29 ( 3 ): 165 - 172 , https://doi.org/10.1080/08997659.2017.1349006 https://doi.org/10.1080/08997659.2017.1349006 .

Guardiola F A , Gónzalez-Párraga P , Meseguer J et al . 2014 . Modulatory effects of deltamethrin-exposure on the immune status, metabolism and oxidative stress in gilthead seabream ( Sparus aurata L.) . Fish & Shellfish Immunology , 36 ( 1 ): 120 - 129 , https://doi.org/10.1016/j.fsi.2013.10.020 https://doi.org/10.1016/j.fsi.2013.10.020 .

Halliwell B . 2012 . Free radicals and antioxidants: updating a personal view . Nutrition Reviews , 70 ( 5 ): 257 - 265 , https://doi.org/10.1111/j.1753-4887.2012.00476.x https://doi.org/10.1111/j.1753-4887.2012.00476.x .

Han X K , Zheng Y Y , Dai C L et al . 2021 . Effect of polystyrene microplastics and temperature on growth, intestinal histology and immune responses of brine shrimp Artemia franciscana . Journal of Oceanology and Limnology , 39 ( 3 ): 979 - 988 , https://doi.org/10.1007/s00343-020-0118-2 https://doi.org/10.1007/s00343-020-0118-2 .

Hong Y H , Huang Y , Yan G W et al . 2019 . Effects of deltamethrin on the antioxidant defense and heat shock pr otein expression in Chinese mitten crab, Eriocheir sinensis . Environmental Toxicology and Pharmacology , 66 : 1 - 6 , https://doi.org/10.1016/j.etap.2018.12.012 https://doi.org/10.1016/j.etap.2018.12.012 .

Hossain M M , Toltin A C , Gamba L M et al . 2022 . Deltamethrin-evoked ER stress promotes neuroinflammation in the adult mouse hippocampus . Cells , 11 ( 12 ): 1961 , https://doi.org/10.3390/cells11121961 https://doi.org/10.3390/cells11121961 .

Jiang Q , Jiang Z Y , Ao S Q et al . 2021 . Multi-biomarker assessment in the giant freshwater prawn Macrobrachium rosenbergii after deltamethrin exposure . Ecotoxicology and Environmental Safety , 214 : 112067 , https://doi.org/10.1016/j.ecoenv.2021.112067 https://doi.org/10.1016/j.ecoenv.2021.112067 .

Kong Y D , Li M , Guo G L et al . 2021 . Effects of dietary curcumin inhibit deltamethrin-induced oxidative stress, inflammation and cell apoptosis in Channa argus via Nrf2 and NF-κB signaling pathways . Aquaculture , 540 : 736744 , https://doi.org/10.1016/j.aquaculture.2021.736744 https://doi.org/10.1016/j.aquaculture.2021.736744 .

Kumar D , Roy R , Parashar A et al . 2017 . Toxicity assessment of zero valent iron nanoparticles on Artemia salina . Environmental Toxicology , 32 ( 5 ): 1617 - 1627 , https://doi.org/10.1002/tox.22389 https://doi.org/10.1002/tox.22389 .

Li J Y , Jiang H J , Wu P F et al . 2021 . Toxicological effects of deltamethrin on quail cerebrum: weakened antioxidant defense and enhanced apoptosis . Environmental Pollution , 286 : 117319 , https://doi.org/10.1016/j.envpol.2021.117319 https://doi.org/10.1016/j.envpol.2021.117319 .

Li M , Wu X Q , Zou J X et al . 2022 . Dietary α-lipoic acid alleviates deltamethrin-induced immunosuppression and oxidative stress in northern snakehead ( Channa argus ) via Nrf2/NF-κB signaling pathway . Fish & Shellfish Immunology , 127 : 228 - 237 , https://doi.org/10.1016/j.fsi.2022.06.029 https://doi.org/10.1016/j.fsi.2022.06.029 .

Libralato G . 2014 . The case of Artemia spp. in nanoecotoxicology . Marine Environmental Research , 101 : 38 - 43 , https://doi.org/10.1016/j.marenvres.2014.08.002 https://doi.org/10.1016/j.marenvres.2014.08.002 .

Liu X Q , Cheng S , Aroca R et al . 2022 . Arbuscular mycorrhizal fungi induce flavonoid synthesis for mitigating oxidative damage of trifoliate orange under water stress . Environmental and Experimental Botany , 204 : 105089 , https://doi.org/10.1016/j.envexpbot.2022.105089 https://doi.org/10.1016/j.envexpbot.2022.105089 .

Lu Q R , Sun Y Q , Ares I et al . 2019 . Deltamethrin toxicity: a review of oxidative stress and metabolism . Environmental Research , 170 : 260 - 281 , https://doi.org/10.1016/j.envres.2018.12.045 https://doi.org/10.1016/j.envres.2018.12.045 .

Ma C J , Deng Y J , Xiao R et al . 2022 . Anti-fatigue effect of phlorizin on exhaustive exercise-induced oxidative injury mediated by Nrf2/ARE signaling pathway in mice . European Journal of Pharmacology , 918 : 174563 , https://doi.org/10.1016/j.ejphar.2021.174563 https://doi.org/10.1016/j.ejphar.2021.174563 .

Magesh S , Chen Y , Hu L Q . 2012 . Small molecule modulators of Keap1-Nrf2-ARE pathway as potential preventive and therapeutic agents . Medicinal Research Reviews , 32 ( 4 ): 687 - 726 , https://doi.org/10.1002/med.21257 https://doi.org/10.1002/med.21257 .

Matthews R S . 1995 . Artemia salina as a test organism for measuring superoxide-mediated toxicity . Free Radical Biology and Medicine , 18 ( 5 ): 919 - 922 , https://doi.org/10.1016/0891-5849(94)00205-X https://doi.org/10.1016/0891-5849(94)00205-X .

Mei X R , Zhang X Y , Wang Z G et al . 2016 . Insulin sensitivity-enhancing activity of phlorizin is associated with lipopolysaccharide decrease and gut microbiota changes in obese and type 2 diabetes ( db / db ) mice . Journal of Agricultural and Food Chemistry , 64 ( 40 ): 7502 - 7511 , https://doi.org/10.1021/acs.jafc.6b03474 https://doi.org/10.1021/acs.jafc.6b03474 .

Muceniece R , Namniece J , Nakurte I et al . 2016 . Pharmacological research on natural substances in Latvia: focus on lunasin, betulin, polyprenol and phlorizin . Pharmacological Research , 113 : 760 - 770 , https://doi.org/10.1016/j.phrs.2016.03.040 https://doi.org/10.1016/j.phrs.2016.03.040 .

Park S , Park S K . 2022 . Anti-oxidant and anti-aging effects of phlorizin are mediated by DAF-16-induced stress response and autophagy in Caenorhabditis elegans . Antioxidants , 11 ( 10 ): 1996 , https://doi.org/10.3390/antiox11101996 https://doi.org/10.3390/antiox11101996 .

Parlak V . 2018 . Evaluation of apoptosis, oxidative stress responses, AChE activity and body malformations in zebrafish ( Danio rerio ) embryos exposed to deltamethrin . Chemosphere , 207 : 397 - 403 , https://doi.org/10.1016/j.chemosphere.2018.05.112 https://doi.org/10.1016/j.chemosphere.2018.05.112 .

Parsons A E , Escobar-Lux R H , Saevik P N et al . 2020 . The impact of anti-sea lice pesticides, azamethiphos and deltamethrin, on European lobster ( Homarus gammarus ) larvae in the Norwegian marine environment . Environmental Pollution , 264 : 114725 , https://doi.org/10.1016/j.envpol.2020.114725 https://doi.org/10.1016/j.envpol.2020.114725 .

Qu L N , Chen H L , Liu X M et al . 2010 . Protective effects of flavonoids against oxidative stress induced by simulated microgravity in SH-SY5Y cells . Neurochemical Research , 35 ( 9 ): 1445 - 1454 , https://doi.org/10.1007/s11064-010-0205-4 https://doi.org/10.1007/s11064-010-0205-4 .

Radovanović T B , Nasia M , Krizmanić I I et al . 2017 . Sublethal effects of the pyrethroid insecticide deltamethrin on oxidative stress parameters in green toad ( Bufotes viridis L.) . Environmental Toxicology and Chemistry , 36 ( 10 ): 2814 - 2822 , https://doi.org/10.1002/etc.3849 https://doi.org/10.1002/etc.3849 .

Romero A , Ares I , Ramos E et al . 2015 . Evidence for dose-additive effects of a type II pyrethroid mixture. In vitro assessment . Environmental Research , 138 : 58 - 66 , https://doi.org/10.1016/j.envres.2015.02.008 https://doi.org/10.1016/j.envres.2015.02.008 .

Sayeed I , Parvez S , Pandey S et al . 2003 . Oxidative stress biomarkers of exposure to deltamethrin in freshwater fish, Channa punctatus Bloch . Ecotoxicology and Environmental Safety , 56 ( 2 ): 295 - 301 , https://doi.org/10.1016/S0147-6513(03)00009-5 https://doi.org/10.1016/S0147-6513(03)00009-5 .

Shang A , Liu H Y , Luo M et al . 2022 . Sweet tea ( Lithocarpus polystachyus rehd.) as a new natural source of bioactive dihydrochalcones with multiple health benefits . Critical Reviews in Food Science and Nutrition , 62 ( 4 ): 917 - 934 , https://doi.org/10.1080/10408398.2020.1830363 https://doi.org/10.1080/10408398.2020.1830363 .

Shekarchi B , Nekuiefard A , Manaffar R . 2020 . Feeding Artemia larvae with yeast heat shock proteins 82 (HSPs82) to enhance the resistance against abiotic stresses (hyperosmotic and high temperatures) . Iranian Journal of Fisheries Sciences , 19 ( 1 ): 19 - 30 , https://doi.org/10.22092/IJFS.2019.118229 https://doi.org/10.22092/IJFS.2019.118229 .

Shi W B , Zhang D S , Wang L et al . 2019 . Curcumin synergistically potentiates the protective effect of sitagliptin against chronic deltamethrin nephrotoxicity in rats: impact on pro-inflammatory cytokines and Nrf2/Ho-1 pathway . Journal of Biochemical and Molecular Toxicology , 33 ( 10 ): e22386 , https://doi.org/10.1002/jbt.22386 https://doi.org/10.1002/jbt.22386 .

Tian Y , Lu W B , Deng H H et al . 2018 . Phlorizin administration ameliorates cognitive deficits by reducing oxidative stress, tau hyper-phosphorylation, and neuroinflammation in a rat model of Alzheimer's disease . Journal of Food Biochemistry , 42 ( 6 ): e12644 , https://doi.org/10.1111/jfbc.12644 https://doi.org/10.1111/jfbc.12644 .

Toumi H , Boumaiza M , Millet M et al . 2013 . Effects of deltamethrin (pyrethroid insecticide) on growth, reproduction, embryonic development and sex differentiation in two strains of Daphnia magna (Crustacea, Cladocera) . Science of the Total Environment , 458 - 460 : 47 - 53 , https://doi.org/10.1016/j.scitotenv.2013.03.085 https://doi.org/10.1016/j.scitotenv.2013.03.085 .

Varó I , Perini A , Torreblanca A et al . 2019 . Time-dependent effects of polystyrene nanoparticles in brine shrimp Artemia franciscana at physiological, biochemical and molecular levels . Science of the Total Environment , 675 : 570 - 580 , https://doi.org/10.1016/j.scitotenv.2019.04.157 https://doi.org/10.1016/j.scitotenv.2019.04.157 .

Viciano E , Monroig Ó , Barata C et al . 2017 . Antioxidant activity and lipid peroxidation in Artemia nauplii enriched with DHA-rich oil emulsion and the effect of adding an external antioxidant based on hydroxytyrosol . Aquaculture Research , 48 ( 3 ): 1006 - 1019 , https://doi.org/10.1111/are.12943 https://doi.org/10.1111/are.12943 .

Wang H , Cheng J , Wang H L et al . 2019a . Protective effect of apple phlorizin on hydrogen peroxide-induced cell damage in HepG2 cells . Journal of Food Biochemistry , 43 ( 12 ): e13052 , https://doi.org/10.1111/jfbc.13052 https://doi.org/10.1111/jfbc.13052 .

Wang H , Sun Z O , Liu D et al . 2019b . Apple phlorizin attenuates oxidative stress in Drosophila melanogaster . Journal of Food Biochemistry , 43 ( 3 ): e12744 , https://doi.org/10.1111/jfbc.12744 https://doi.org/10.1111/jfbc.12744 .

Wang M C , Bohmann D , Jasper H . 2003 . JNK signaling confers tolerance to oxidative stress and extends lifespan in Drosophila . Developmental Cell , 5 ( 5 ): 811 - 816 , https://doi.org/10.1016/S1534-5807(03)00323-X https://doi.org/10.1016/S1534-5807(03)00323-X .

Yang C , Lim W , Song G . 2020 . Mediation of oxidative stress toxicity induced by pyrethroid pesticides in fish . Comparative Biochemistry and Physiology Part C : Toxicology & Pharmacology , 234 : 108758 , https://doi.org/10.1016/j.cbpc.2020.108758 https://doi.org/10.1016/j.cbpc.2020.108758 .

Yang X , Fang Y , Hou J B et al . 2022 . The heart as a target for deltamethrin toxicity: inhibition of Nrf2/HO-1 pathway induces oxidative stress and results in inflammation and apoptosis . Chemosphere , 300 : 134479 , https://doi.org/10.1016/j.chemosphere.2022.134479 https://doi.org/10.1016/j.chemosphere.2022.134479 .

Yang X D , Bai Z F , Zhang Y et al . 2021 . Flavonoids-rich extract from Bidens bipinnata L. protects pancreatic β-cells against oxidative stress-induced apoptosis through intrinsic and extrinsic pathways . Journal of Ethnopharmacology , 275 : 114097 , https://doi.org/10.1016/j.jep.2021.114097 https://doi.org/10.1016/j.jep.2021.114097 .

Yavuz O , Aksoy A , Das Y K et al . 2015 . Subacute oral toxicity of combinations of selected synthetic pyrethroids, piperonyl butoxide, and tetramethrin in rats . Toxicology and Industrial Health , 31 ( 4 ): 289 - 297 , https://doi.org/10.1177/0748233712469651 https://doi.org/10.1177/0748233712469651 .

Yonar M E , Yonar S M , İspir Ü et al . 2019 . Effects of curcumin on haematological values, immunity, antioxidant status and resistance of rainbow trout ( Oncorhynchus mykiss ) against Aeromonas salmonicida subsp. achromogenes . Fish & Shellfish Immunology , 89 : 83 - 90 , https://doi.org/10.1016/j.fsi.2019.03.038 https://doi.org/10.1016/j.fsi.2019.03.038 .

Zeng X Q , Du Z J , Ding X M et al . 2021 . Protective effects of dietary flavonoids against pesticide-induced toxicity: a review . Trends in Food Science & Technology , 109 : 271 - 279 , https://doi.org/10.1016/j.tifs.2021.01.046 https://doi.org/10.1016/j.tifs.2021.01.046 .

Zhai Y M , Dang Y Y , Gao W K et al . 2015 . P38 and JNK signal pathways are involved in the regulation of phlorizin against UVB-induced skin damage . Experimental Dermatology , 24 ( 4 ): 275 - 279 , https://doi.org/10.1111/exd.12642 https://doi.org/10.1111/exd.12642 .

Zhang C , Zhang Q , Pang Y Y et al . 2019 . The protective effects of melatonin on oxidative damage and the immune system of the Chinese mitten crab ( Eriocheir sinensis ) exposed to deltamethrin . Science of the Total Environment , 653 : 1426 - 1434 , https://doi.org/10.1016/j.scitotenv.2018.11.063 https://doi.org/10.1016/j.scitotenv.2018.11.063 .

Zhang C Y , Chi C , Liu J D et al . 2020a . Protective effects of dietary arginine against oxidative damage and hepatopancreas immune responses induced by T-2 toxin in Chinese mitten crab ( Eriocheir sinensis ) . Fish & Shellfish Immunology , 104 : 447 - 456 , https://doi.org/10.1016/j.fsi.2020.06.034 https://doi.org/10.1016/j.fsi.2020.06.034 .

Zhang H W , Chen H Y , Li J et al . 2020b . Hirudin protects against isoproternol-induced myocardial infraction by alleviating oxidative via an Nrf2 dependent manner . International Journal of Biological Macromolecules , 162 : 425 - 435 , https://doi.org/10.1016/j.ijbiomac.2020.06.097 https://doi.org/10.1016/j.ijbiomac.2020.06.097 .

Zhang J K , Li M C , Zhao T R et al . 2022 . E Se tea alleviates acetaminophen-induced liver injury by activating the Nrf2 signaling pathway . Food & Function , 13 ( 13 ): 7240 - 7250 , https://doi.org/10.1039/D1FO02491D https://doi.org/10.1039/D1FO02491D .

Zhang W , Chen S Q , Fu H L et al . 2021 . Hypoglycemic and hypolipidemic activities of phlorizin from Lithocarpus polystachyus Rehd in diabetes rats . Food Science & Nutrition , 9 ( 4 ): 1989 - 1996 , https://doi.org/10.1002/fsn3.2165 https://doi.org/10.1002/fsn3.2165 .

Zhou L H , Zhou M Q , Tan H D et al . 2020 . Cypermethrin-induced cortical neurons apoptosis via the Nrf2/ARE signaling pathway . Pesticide Biochemistry and Physiology , 165 : 104547 , https://doi.org/10.1016/j.pestbp.2020.02.013 https://doi.org/10.1016/j.pestbp.2020.02.013 .

Zhou S , Dong J , Liu Y T et al . 2021 . Effects of acute deltamethrin exposure on kidney transcriptome and intestinal microbiota in goldfish ( Carassius auratus ) . Ecotoxicology and Environmental Safety , 225 : 112716 , https://doi.org/10.1016/j.ecoenv.2021.112716 https://doi.org/10.1016/j.ecoenv.2021.112716 .

Zhou Y P , Jiang Z L , Lu H Y et al . 2019 . Recent advances of natural polyphenols activators for Keap1-Nrf2 signaling pathway . Chemistry & Biodiversity , 16 ( 11 ): e1900400 , https://doi.org/10.1002/cbdv.201900400 https://doi.org/10.1002/cbdv.201900400 .

Zhu B , Zhu S , Li J et al . 2018 . The developmental toxicity, bioaccumulation and distribution of oxidized single walled carbon nanotubes in Artemia salina . Toxicology Research , 7 ( 5 ): 897 - 906 , https://doi.org/10.1039/C8TX00084K https://doi.org/10.1039/C8TX00084K .

Views

Downloads

CSCD

Alert me when the article has been cited

Submit

Tools

Publicity Resources

Marine fungal metabolite butyrolactone I improves Aβ_1-42-induced cognitive impairment in mice via gut-brain axial microbiota remodeling, anti-inflammation, and antioxidation

Size-dependent toxicity of microplastics induced gut cell apoptosis in brine shrimp Artemia parthenogenetica through p53 signaling pathway

The impacts of PVC microplastics on physiology and transcriptomic responses of pearl oyster Pinctada fucata martensii

Heat stress induced hepatocyte apoptosis in largemouth bass Micropterus salmoides via IRE1α/TRAF2/ASK1/JNK pathway

Research on Unsteady Characteristics ofUnderwater Supersonic Gas Jet

Related Author

Fuyan YANG

Longjian ZHOU

Jiahang DENG

Yuan WANG

Zhiyou YANG

Yongping ZHANG

Yayue LIU

Yi ZHANG

Related Institution

Collaborative Innovation Center of Seafood Deep Processing, Dalian Polytechnic University

Southern Marine Science and Engineering Guangdong Laboratory

Guangdong Provincial Key Laboratory of Aquatic Product Processing and Safety, Guangdong Provincial Engineering Laboratory for Marine Biological Products, Marine Biomedicine R&D Center at Shenzhen Institute of Guangdong Ocean University, Zhanjiang Municipal Key Laboratory of Marine Drugs and Nutrition for Brain Health, Research Institute for Marine Drugs and Nutrition, College of Food Science and Technology, Guangdong Ocean University

Asian Regional Artemia Reference Center, College of Marine and Environmental Sciences, Tianjin University of Science and Technology

Key Laboratory of Marine Resource Chemistry and Food Technology (TUST), Ministry of Education, Tianjin University of Science and Technology

Address：Editorial Office of JOL, 88 Haijun Rd. Qingdao, 266000, China
Tel：+86-532-82898754 Email：jol@qdio.ac.cn
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备09064830号-19 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰

Phlorizin alleviates deltamethrin-induced oxidative stress in brine shrimp Artemia

DOI：10.1007/s00343-023-2387-z

摘要

Abstract

关键词

Keywords

references