First observation of domoic acid and its isomers in shellfish samples from Shandong Province, China

Guanchao ZHENG; Haiyan WU; Mengmeng GUO; Jixing PENG; Yuxiu ZHAI; Zhijun TAN

doi:10.1007/s00343-022-2104-3

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First observation of domoic acid and its isomers in shellfish samples from Shandong Province, China

Marine algal toxins | Updated：2023-05-20

- First observation of domoic acid and its isomers in shellfish samples from Shandong Province, China
- Journal of Oceanology and Limnology Vol. 40, Issue 6, Pages: 2231-2241(2022)
- Affiliations：
  
  1.Key Laboratory of Testing and Evaluation for Aquatic Product Safety and Quality, Ministry of Agriculture and Rural Affairs, Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Qingdao 266071, China
  2.Pilot National Laboratory for Marine Science and Technology(Qingdao), Qingdao 266237, China
  3.Collaborative Innovation Center of Seafood Deep Processing, Dalian Polytechnic University, Dalian 116034, China
- Author bio：
  
  Zhijun TAN, E-mail: tanzj@ysfri.ac.cn
- Funds：
- DOI：10.1007/s00343-022-2104-3
  CLC：
- Received：18 March 2022，
  
  Accepted：25 May 2022，
  
  Online First：06 June 2022，
  
  Published：2022-11
- Accepted：
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Guanchao ZHENG, Haiyan WU, Mengmeng GUO, et al. First observation of domoic acid and its isomers in shellfish samples from Shandong Province, China[J]. Journal of Oceanology and Limnology, 2022, 40(6): 2231-2241.
DOI：

Guanchao ZHENG, Haiyan WU, Mengmeng GUO, et al. First observation of domoic acid and its isomers in shellfish samples from Shandong Province, China[J]. Journal of Oceanology and Limnology, 2022, 40(6): 2231-2241. DOI： 10.1007/s00343-022-2104-3.

摘要

Abstract

Atotal of 133 shellfish samples were collected in seven cities of Shandong Province

China

from May to October

2019. The domoic acid (DA) concentrations were determined by liquid chromatography-tandem mass spectrometry (LC-MS/MS)

and their distribution characteristics were investigated. DA concentration was detected high in over 1/3 (36.1%) of the samples of four kinds of shellfish in all three seasons in range from 0 to 102 μg/kg. The highest DA concentrations were 102

101

36.7

and 10.2 μg/kg in

Crassostrea gigas

Chlamys farreri

Mactra veneriformis

and

Mytilus edulis

respectively. Geographically

Yantai (22.0 μg/kg) and Weihai (16.9 μg/kg) showed relatively high concentrations of DA

whereas Rizhao and Dongying presented only 0.85- and 1.76-μg/kg DA

respectively. DA concentrations in the shellfish samples were strongly related to seasonal changes

being significantly higher in autumn and summer than that in spring. The DA risk exposure assessments indicate that dietary seafood consumption did not pose a health threat to general human population. In addition

three isomers (isoA

isoD

isoE) and 5'-epimer DA were detected in 3.00%Ƀ15.80% of the shellfish samples. This study is the first to observe DA and its isomers in shellfish samples of Shandong Province. The results demonstrate that DA contamination is very common and should be continuously monitored.

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references

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