Genome-wide evolution of MAPKs family and their expression in response to bacterial infection in seahorse <italic style="font-style: italic">Hippocampus erectus</italic>

Kai WANG; Xin WANG; Qiang ZOU; Han JIANG; Rongrong ZHANG; Yanan TIAN; Lele ZHANG; Qiang LIN

doi:10.1007/s00343-020-0332-y

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Genome-wide evolution of MAPKs family and their expression in response to bacterial infection in seahorse Hippocampus erectus

Biology | Updated：2023-05-20

- Genome-wide evolution of MAPKs family and their expression in response to bacterial infection in seahorse Hippocampus erectus
- Journal of Oceanology and Limnology Vol. 39, Issue 6, Pages: 2309-2321(2021)
- Affiliations：
  
  1.School of Agriculture, Ludong University, Yantai 264025, China
  2.CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China
  3.Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), Guangzhou 511458, China
  4.Yantai Branch of Shandong Technology Transfer Center, Chinese Academy of Sciences, Yantai 264003, China
  5.University of Chinese Academy of Sciences, Beijing 100049, China
- Author bio：
  
  Kai WANG, E-mail: wangkyt@163.com
  Qiang LIN, E-mail: linqiang@scsio.ac.cn
- Funds：
- DOI：10.1007/s00343-020-0332-y
  CLC：
- Received：25 August 2020，
  
  Accepted：09 November 2020，
  
  Online First：25 November 2020，
  
  Published：2021-11
- Accepted：
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Kai WANG, Xin WANG, Qiang ZOU, et al. Genome-wide evolution of MAPKs family and their expression in response to bacterial infection in seahorse Hippocampus erectus[J]. Journal of Oceanology and Limnology, 2021, 39(6): 2309-2321.
DOI：

Kai WANG, Xin WANG, Qiang ZOU, et al. Genome-wide evolution of MAPKs family and their expression in response to bacterial infection in seahorse Hippocampus erectus[J]. Journal of Oceanology and Limnology, 2021, 39(6): 2309-2321. DOI： 10.1007/s00343-020-0332-y.

摘要

Abstract

Seahorses have evolved many unique biological traits

including a male brood pouch

the absence of caudal and pelvic fins

and the lack of spleen and gut-associated lymphatic tissue. The mitogenactivated protein kinases (MAPKs) are known to be involved in various important biological processes including growth

differentiation

immunity

and stress responses. Therefore

we hypothesized that the adaptive evolution and expression of the MAPK gene family in seahorse may differ from those of other teleost species. We identified positive selection sites in the

erk2

erk5

jnk1

and

p38α

MAPK genes of the lined seahorse

Hippocampus erectus

and tiger-tailed seahorse

Hippocampus comes

. A novel expression profile of MAPK cascade genes was found in seahorse larvae during the first day after birth based on the RNA-seq data of

erectus

which reflected vital signs of immune response to its parental immune system. The expression patterns of the four positively selected MAPK genes were analyzed following the bacterial challenge of

Vibrio fortis

revealing their upregulation pattern in brood pouch and other immune tissues. This study enriched our knowledge of the evolution of the

erectus

MAPK subfamilies

and could help better understanding the functional role of MAPKs in teleosts.

关键词

Keywords

references

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⁰

Genome-wide evolution of MAPKs family and their expression in response to bacterial infection in seahorse Hippocampus erectus

DOI：10.1007/s00343-020-0332-y

摘要

Abstract

关键词

Keywords

references