Antioxidant bisabolane-type sesquiterpenoids from algalderived fungus <italic style="font-style: italic">Aspergillus sydowii</italic> EN-434

Xueyi HU; Xiaoming LI; Linghong MENG; Bingui WANG

doi:10.1007/s00343-020-0049-y

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Antioxidant bisabolane-type sesquiterpenoids from algalderived fungus Aspergillus sydowii EN-434

Chemistry | Updated：2023-04-27

- Antioxidant bisabolane-type sesquiterpenoids from algalderived fungus Aspergillus sydowii EN-434
- Journal of Oceanology and Limnology Vol. 38, Issue 5, Pages: 1532-1536(2020)
- Affiliations：
  
  1.Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, and Laboratory of Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao 266071, China
  2.College of Earth Science, University of Chinese Academy of Sciences, Beijing 100049, China
  3.Center for Ocean Mega-Science, Chinese Academy of Sciences, Qingdao 266071, China
- Author bio：
  
  MENG Linghong, menglh@qdio.ac.cn
  WANG Bingui, wangbg@qdio.ac.cn
- Funds：
- DOI：10.1007/s00343-020-0049-y
  CLC：
- Received：23 January 2020，
  
  Accepted：03 April 2020，
  
  Online First：05 May 2020，
  
  Published：2020-09
- Accepted：
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Xueyi HU, Xiaoming LI, Linghong MENG, et al. Antioxidant bisabolane-type sesquiterpenoids from algalderived fungus Aspergillus sydowii EN-434[J]. Journal of Oceanology and Limnology, 2020, 38(5): 1532-1536.
DOI：

Xueyi HU, Xiaoming LI, Linghong MENG, et al. Antioxidant bisabolane-type sesquiterpenoids from algalderived fungus Aspergillus sydowii EN-434[J]. Journal of Oceanology and Limnology, 2020, 38(5): 1532-1536. DOI： 10.1007/s00343-020-0049-y.

摘要

Abstract

A new aromatic bisabolene-type sesquiterpenoid (7

)-8-hydroxysydowic acid (

)

together with a pair of new bisabolene derivative (±)-(7

)-10-hydroxysydowic acid (

)

as well as two known analogues hydroxysydonic acid (

) and sydowic acid (

) were isolated and identified from the endophytic fungal strain

Aspergillus sydowii

EN-434 that was obtained from the marine red alga

Symphyocladia latiuscula

. Their structures were elucidated by nuclear magnetic resonance (NMR)

high resolution electrospray ionization mass spectroscopy (HRESIMS)

and quantum chemical electronic circular dichroism (ECD) calculations as well as comparison of the data with literature reports. Compound

exhibited potent DPPH free radical scavenging activity with IC

value of 113.5 μmol/L.

关键词

Keywords

references

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Related Institution

University of Chinese Academy of Sciences

Laboratory for Marine Biology and Biotechnology, Qingdao Marine Science and Technology Center

CAS and Shandong Province Key Laboratory of Experimental Marine Biology, Center for Ocean Mega-Science, Institute of Oceanology, Chinese Academy of Sciences

Jiangsu Innovation Center of Marine Bioresources, Jiangsu Coast Development Investment Co., Ltd., Jiangsu Coast Development Group Co., Ltd.

College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology

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Antioxidant bisabolane-type sesquiterpenoids from algalderived fungus Aspergillus sydowii EN-434

DOI：10.1007/s00343-020-0049-y

摘要

Abstract

关键词

Keywords

references