Tumor necrosis factor-alpha (TNF-α) in spotted halibut <italic style="font-style: italic">Verasper variegatus</italic> at the embryonic and metamorphic stages

Zan LI; Xiumei LIU; Xinxin DU; Kai ZHANG; Yan CHEN; Xubo WANG; Zhigang WANG; Haiyang YU; Quanqi ZHANG

doi:10.1007/s00343-019-8289-4

Your Location：

Home >

Browse articles >

Tumor necrosis factor-alpha (TNF-α) in spotted halibut Verasper variegatus at the embryonic and metamorphic stages

Biology | Updated：2023-04-27

- Tumor necrosis factor-alpha (TNF-α) in spotted halibut Verasper variegatus at the embryonic and metamorphic stages
- Journal of Oceanology and Limnology Vol. 38, Issue 2, Pages: 454-466(2020)
- Affiliations：
  
  1.School of Agriculture, Ludong University, Yantai 264025, China
  2.College of Life Sciences, Yantai University, Yantai 264005, China
  3.Key Laboratory of Marine Genetics and Breeding, Ministry of Education, College of Marine Life Science, Ocean University of China, Qingdao 266003, China
- Author bio：
  
  LI Zan, lizanlxm@163.com
- Funds：
- DOI：10.1007/s00343-019-8289-4
  CLC：
- Received：08 November 2018，
  
  Accepted：28 January 2019，
  
  Online First：30 June 2019，
  
  Published：2020-02
- Accepted：
Scan QR Code
Zan LI, Xiumei LIU, Xinxin DU, et al. Tumor necrosis factor-alpha (TNF-α) in spotted halibut Verasper variegatus at the embryonic and metamorphic stages[J]. Journal of Oceanology and Limnology, 2020, 38(2): 454-466.
DOI：

Zan LI, Xiumei LIU, Xinxin DU, et al. Tumor necrosis factor-alpha (TNF-α) in spotted halibut Verasper variegatus at the embryonic and metamorphic stages[J]. Journal of Oceanology and Limnology, 2020, 38(2): 454-466. DOI： 10.1007/s00343-019-8289-4.

摘要

Abstract

As an aquatic fish

the spotted halibut

Verasper variegatus

is highly susceptible to bacterial and virus infections. Tumor necrosis factor-alpha (TNF-α) as a cytokine could control the inflammatory responses. The functions of TNF-α in many species have been widely studied

particularly in mammals. However

little is known about the TNF-α functions in

V. variegatus

. We first cloned and sequenced the TNF-α gene in

V. variegatus

(VvTNF-α). The two conserved cysteine residues

transmembrane sequence

Thr-Leu motif

and TNF family signature

as well as the TA-rich motifs of its proteins related to inflammatory responses had high similarity to those of the other teleost and mammalian TNF-α. The phylogenetic analysis showed that VvTNF-α was consistent with TNF-α genes of other vertebrates. The VvTNF-α transcripts were extensively distributed in the peripheral blood leukocytes (PBLs)

spleen

and gill

indicating that the VvTNF-α had a role in immune function. Furthermore

treatment with pathogen-associated molecular patterns (PAMPs) could induce a rapid and significant increase of VvTNF-α in the PBLs

which reveals that VvTNF-α does participate in the host immune responses against bacterial and viral pathogens. We found that VvTNF-α had an interesting expression pattern during metamorphosis

showing that the flatfish TNF-α may have some novel functions during specific developmental stages. In addition

the 3D structure prediction of VvTNF-α provided an indication of how it is likely to interact with other proteins. Therefore

VvTNF-α has multiple functions

and provides valuable information to explore novel functions of TNF-α.

关键词

Keywords

references

R D Acton , P S Dahlberg , M E Uknis , H G Klaerner , G S Fink , J G Norman , D L Dunn . Differential sensitivity to Escherichia coli infection in mice lacking tumor necrosis factor p55 or interleukin-1 p80 receptors . Archives of Surgery , 1996 . 131 ( 11 ): 1 216 - 1 221 . DOI: 10.1001/archsurg.1996.01430230098017 http://doi.org/10.1001/archsurg.1996.01430230098017 .

G Aust , M Heuer , S Laue , I Lehmann , A Hofmann , N E Heldin , W A Scherbaum . Expression of tumour necrosis factor-alpha (TNF-α) mRNA and protein in pathological thyroid tissue and carcinoma cell lines . Clinical and Experimental Immunology , 1996 . 105 ( 1 ): 148 - 154 . DOI: 10.1046/j.1365-2249.1996.d01-726.x http://doi.org/10.1046/j.1365-2249.1996.d01-726.x .

A A Beg , D Baltimore . An essential role for NF-κB in preventing TNF-α-induced cell death . Science , 1996 . 274 ( 5288 ): 782 - 784 . DOI: 10.1126/science.274.5288.782 http://doi.org/10.1126/science.274.5288.782 .

C P Blobel . Metalloprotease-disintegrins:links to cell adhesion and cleavage of TNFα and Notch . Cell , 1997 . 90 ( 4 ): 589 - 592 . DOI: 10.1016/S0092-8674(00)80519-X http://doi.org/10.1016/S0092-8674(00)80519-X .

M A Campinho , N Silva , G E Sweeney , D M Power . Molecular, cellular and histological changes in skin from a larval to an adult phenotype during bony fish metamorphosis . Cell and Tissue Research , 2007 . 327 ( 2 ): 267 - 284 . http://cn.bing.com/academic/profile?id=72f6529da966c7135e34c99514923cd0&encoded=0&v=paper_preview&mkt=zh-cn http://cn.bing.com/academic/profile?id=72f6529da966c7135e34c99514923cd0&encoded=0&v=paper_preview&mkt=zh-cn , .

G Camussi , E Albano , C Tetta , F Bussolino . The molecular action of tumor necrosis factor-α . European Journal of Biochemistry , 1991 . 202 ( 1 ): 3 - 14 . http://d.old.wanfangdata.com.cn/OAPaper/oai_pubmedcentral.nih.gov_304855 http://d.old.wanfangdata.com.cn/OAPaper/oai_pubmedcentral.nih.gov_304855 , .

D Caput , B Beutler , K Hartog , R Thayer , S Brown-Shimer , A Cerami . Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators . Proceedings of the National Academy of Sciences of the United States of America , 1986 . 83 ( 6 ): 1 670 - 1 674 . DOI: 10.1073/pnas.83.6.1670 http://doi.org/10.1073/pnas.83.6.1670 .

M X Chang , P Nie , H X Xie , G L Wang , Y Gao . Characterization and expression analysis of TNF-related apoptosis inducing ligand (TRAIL) in grass carp Ctenopharyngodon idella . Veterinary Immunology and Immunopathology , 2006 . 110 ( 1-2 ): 51 - 63 . DOI: 10.1016/j.vetimm.2005.09.003 http://doi.org/10.1016/j.vetimm.2005.09.003 .

W Chu . Tumor necrosis factor . Cancer Letters , 2013 . 328 ( 2 ): 222 - 225 . DOI: 10.1016/j.canlet.2012.10.014 http://doi.org/10.1016/j.canlet.2012.10.014 .

J M Covello , S Bird , R N Morrison , S C Battaglene , C J Secombes , B F Nowak . Cloning and expression analysis of three striped trumpeter ( Latris lineata ) pro-inflammatory cytokines, TNF-α, IL-1β and IL-8, in response to infection by the ectoparasitic, Chondracanthus goldsmidi . Fish & Shellfish Immunology , 2009 . 26 ( 5 ): 773 - 786 . DOI: 10.1016/j.fsi.2009.03.012 http://doi.org/10.1016/j.fsi.2009.03.012 .

E G De Jesus , T Hirano , Y Inui . Changes in cortisol and thyroid hormone concentrations during early development and metamorphosis in the Japanese flounder, Paralichthys olivaceus . General and Comparative Endocrinology , 1991 . 82 ( 3 ): 369 - 376 . DOI: 10.1016/0016-6480(91)90312-T http://doi.org/10.1016/0016-6480(91)90312-T .

A E Ellis . Innate host defense mechanisms of fish against viruses and bacteria . Developmental & Comparative Immunology , 2001 . 25 ( 8-9 ): 827 - 839 . http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=caf0c533ac5a90cd9daacc1337d532f5 http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=caf0c533ac5a90cd9daacc1337d532f5 , .

M Forlenza , S Magez , J P Scharsack , A Westphal , H F J Savelkoul , G F Wiegertjes . Receptor-mediated and lectinlike activities of carp ( Cyprinus carpio ) TNF-α . Journal of Immunology , 2009 . 183 ( 8 ): 5 319 - 5 332 . DOI: 10.4049/jimmunol.0901780 http://doi.org/10.4049/jimmunol.0901780 .

J García-Castillo , E Chaves-Pozo , P Olivares , P Pelegrín , J Meseguer , V Mulero . The tumor necrosis factor α of the bony fish seabream exhibits the in vivo proinflammatory and proliferative activities of its mammalian counterparts, yet it functions in a speciesspecific manner . Cellular and Molecular Life Sciences CMLS , 2004 . 61 ( 11 ): 1 331 - 1 340 . DOI: 10.1007/s00018-004-4068-1 http://doi.org/10.1007/s00018-004-4068-1 .

J García-Castillo , P Pelegrín , V Mulero , J Meseguer . Molecular cloning and expression analysis of tumor necrosis factor α from a marine fish reveal its constitutive expression and ubiquitous nature . Immunogenetics , 2002 . 54 ( 3 ): 200 - 207 . DOI: 10.1007/s00251-002-0451-y http://doi.org/10.1007/s00251-002-0451-y .

L Grayfer , J G Walsh , M Belosevic . Characterization and functional analysis of goldfish ( Carassius auratus L . )tumor necrosis factor-alpha. Developmental & Comparative Immunology , 2008 . 32 ( 5 ): 532 - 543 . DOI: 10.1016/j.dci.2007.09.009 http://doi.org/10.1016/j.dci.2007.09.009 .

J Han , T Brown , B Beutler . Endotoxin-responsive sequences control cachectin/tumor necrosis factor biosynthesis at the translational level . Journal of Experimental Medicine , 1990 . 171 ( 2 ): 465 - 475 . DOI: 10.1084/jem.171.2.465 http://doi.org/10.1084/jem.171.2.465 .

J Hawiger . Innate immunity and inflammation:a transcriptional paradigm . Immunologic Research , 2001 . 23 ( 2-3 ): 99 - 109 . DOI: 10.1385/IR:23:2-3:099 http://doi.org/10.1385/IR:23:2-3:099 .

I Hirono , B H Nam , T Kurobe , T Aoki . Molecular cloning, characterization, and expression of TNF cDNA and gene from Japanese flounder Paralychthys olivaceus . Journal of Immunology , 2000 . 165 ( 8 ): 4 423 - 4 427 . DOI: 10.4049/jimmunol.165.8.4423 http://doi.org/10.4049/jimmunol.165.8.4423 .

S Hong , R G Li , Q Q Xu , C J Secombes , T H Wang . Two types of TNF-α Exist in teleost fish:phylogeny, expression, and bioactivity analysis of Type-Ⅱ TNF-α3 in rainbow trout Oncorhynchus mykiss . Journal of Immunology , 2013 . 191 ( 12 ): 5 959 - 5 972 . DOI: 10.4049/jimmunol.1301584 http://doi.org/10.4049/jimmunol.1301584 .

S D Hwang , S H Shim , M Kwon , Y S Chae , W J Shim , J H Jung , J W Kim , C I Park . Molecular cloning and expression analysis of two lipopolysaccharide-induced TNF-α factors (LITAFs) from rock bream, Oplegnathus fasciatus . Fish & Shellfish Immunology , 2014 . 36 ( 2 ): 467 - 474 . DOI: 10.1016/j.fsi.2013.12.023 http://doi.org/10.1016/j.fsi.2013.12.023 .

H T Idriss , J H Naismith . TNFα and the TNF receptor superfamily:structure-function relationship(s) . Microscopy Research and Technique , 2000 . 50 ( 3 ): 184 - 195 . DOI: 10.1002/1097-0029(20000801)50:3<184::AID-JEMT2>3.0.CO;2-H http://doi.org/10.1002/1097-0029(20000801)50:3<184::AID-JEMT2>3.0.CO;2-H .

Y Inui , S Miwa . Thyroid hormone induces metamorphosis of flounder larvae . General and Comparative Endocrinology , 1985 . 60 ( 3 ): 450 - 454 . DOI: 10.1016/0016-6480(85)90080-2 http://doi.org/10.1016/0016-6480(85)90080-2 .

C H Jang , J H Choi , M S Byun , D M Jue . Chloroquine inhibits production of TNF-α, IL-1β and IL-6 from lipopolysaccharide-stimulated human monocytes/macrophages by different modes . Rheumatology , 2006 . 45 ( 6 ): 703 - 710 . DOI: 10.1093/rheumatology/kei282 http://doi.org/10.1093/rheumatology/kei282 .

S A Kalashnikova , A N Goryachev , V V Novochadov , A I Shchyogolev . Thyroid modulation of TNFdependent apoptosis and formation of chronic liver disease in endogenous intoxication in rats . Bulletin of Experimental Biology and Medicine , 2009 . 147 ( 2 ): 240 - 244 . DOI: 10.1007/s10517-009-0484-4 http://doi.org/10.1007/s10517-009-0484-4 .

B S Kim , B H Nam , J W Kim , H J Park , J H Song , C I Park . Molecular characterisation and expression analysis of a fish-egg lectin in rock bream, and its response to bacterial or viral infection . Fish & Shellfish Immunology , 2011 . 31 ( 6 ): 1 201 - 1 207 . http://d.old.wanfangdata.com.cn/Periodical/zhek201007011 http://d.old.wanfangdata.com.cn/Periodical/zhek201007011 , .

E Kiss-Toth , E Harlock , D Lath , T Quertermous , J M Wilkinson . A TNF Variant that associates with susceptibility to musculoskeletal disease modulates thyroid hormone receptor binding to control promoter activation . PLoS One , 2013 . 8 ( 9 ): e76034 DOI: 10.1371/journal.pone.0076034 http://doi.org/10.1371/journal.pone.0076034 .

P H M Klaren , Y S Wunderink , M Yúfera , J M Mancera , G Flik . The thyroid gland and thyroid hormones in Senegalese sole ( Solea senegalensis ) during early development and metamorphosis . General and Comparative Endocrinology , 2008 . 155 ( 3 ): 686 - 694 . DOI: 10.1016/j.ygcen.2007.09.014 http://doi.org/10.1016/j.ygcen.2007.09.014 .

H J Li , J F Fan , S X Liu , Q Yang , G Q Mu , C B He . Characterization of a myostatin gene (MSTN1) from spotted halibut ( Verasper variegatus ) and association between its promoter polymorphism and individual growth performance . Comparative Biochemistry and Physiology Part B:Biochemistry and Molecular Biology , 2012 . 161 ( 4 ): 315 - 322 . DOI: 10.1016/j.cbpb.2011.12.008 http://doi.org/10.1016/j.cbpb.2011.12.008 .

H J Li , L X Jiang , J B Han , H Su , Q Yang , C B He . Major histocompatibility complex class IIA and IIB genes of the spotted halibut Verasper variegatus :genomic structure, molecular polymorphism, and expression analysis . Fish Physiology and Biochemistry , 2011 . 37 ( 4 ): 767 - 780 . DOI: 10.1007/s10695-011-9476-1 http://doi.org/10.1007/s10695-011-9476-1 .

M F Li , J Zhang . CsTNF1, a teleost tumor necrosis factor that promotes antibacterial and antiviral immune defense in a manner that depends on the conserved receptor binding site . Developmental & Comparative Immunology , 2016 . 55 65 - 75 . http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=e7cbd5ee16085206a1dc439241df4a9f http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=e7cbd5ee16085206a1dc439241df4a9f , .

Y W Liu , W K Chan . Thyroid hormones are important for embryonic to larval transitory phase in zebrafish . Differentiation , 2002 . 70 ( 1 ): 36 - 45 . DOI: 10.1046/j.1432-0436.2002.700104.x http://doi.org/10.1046/j.1432-0436.2002.700104.x .

R M Locksley , N Killeen , M J Lenardo . The TNF and TNF receptor superfamilies:integrating mammalian biology . Cell , 2001 . 104 ( 4 ): 487 - 501 . DOI: 10.1016/S0092-8674(01)00237-9 http://doi.org/10.1016/S0092-8674(01)00237-9 .

H Loetscher , M Steinmetz , W Lesslauer . Tumor necrosis factor:receptors and inhibitors . Cancer Cells , 1991 . 3 ( 6 ): 221 - 226 . http://cn.bing.com/academic/profile?id=63fe88d3750a8885223e6cbe94c0a0a4&encoded=0&v=paper_preview&mkt=zh-cn http://cn.bing.com/academic/profile?id=63fe88d3750a8885223e6cbe94c0a0a4&encoded=0&v=paper_preview&mkt=zh-cn , .

O Marchand , M Duffraisse , G Triqueneaux , R Safi , V Laudet . Molecular cloning and developmental expression patterns of thyroid hormone receptors and T3 target genes in the turbot ( Scophtalmus maximus ) during postembryonic development . General and Comparative Endocrinology , 2004 . 135 ( 3 ): 345 - 357 . DOI: 10.1016/j.ygcen.2003.10.012 http://doi.org/10.1016/j.ygcen.2003.10.012 .

A Marchler-Bauer , J B Anderson , F Chitsaz , M K Derbyshire , C DeWeese-Scott , J H Fong , L Y Geer , R C Geer , N R Gonzales , M Gwadz , S Q He , D I Hurwitz , J D Jackson , Z X Ke , C J Lanczycki , C A Liebert , C L Liu , F Lu , S N Lu , G H Marchler , M Mullokandov , J S Song , A Tasneem , N Thanki , R A Yamashita , D C Zhang , N G Zhang , S H Bryant . CDD:specific functional annotation with the Conserved Domain Database . Nucleic Acids Research , 2009 . 37 ( S1 ): 205 - 210 . http://d.old.wanfangdata.com.cn/Periodical/jsjfz200810057 http://d.old.wanfangdata.com.cn/Periodical/jsjfz200810057 , .

A Marchler-Bauer , S H Bryant . CD-Search:protein domain annotations on the fly . Nucleic Acids Research , 2004 . 32 ( S2 ): 327 - 331 . http://d.old.wanfangdata.com.cn/Periodical/jxtsgxk1999z1055 http://d.old.wanfangdata.com.cn/Periodical/jxtsgxk1999z1055 , .

A Marchler-Bauer , M K Derbyshire , N R Gonzales , S N Lu , F Chitsaz , L Y Geer , R C Geer , J N He , M Gwadz , D I Hurwitz , C J Lanczycki , F Lu , G H Marchler , J S Song , N Thanki , Z X Wang , R A Yamashita , D C Zhang , C J Zheng , S H Bryant . CDD:NCBI's conserved domain database . Nucleic Acids Research , 2015 . 43 ( D1 ): D222 - D226 . DOI: 10.1093/nar/gku1221 http://doi.org/10.1093/nar/gku1221 .

A Marchler-Bauer , S N Lu , J B Anderson , F Chitsaz , M K Derbyshire , C DeWeese-Scott , J H Fong , L Y Geer , R C Geer , N R Gonzales , M Gwadz , D I Hurwitz , J D Jackson , Z X Ke , C J Lanczycki , F Lu , G H Marchler , M Mullokandov , M V Omelchenko , C L Robertson , J S Song , N Thanki , R A Yamashita , D C Zhang , N Q Zhang , C J Zheng , S H Bryant . CDD:a conserved domain database for the functional annotation of proteins . Nucleic Acids Research , 2011 . 39 ( D1 ): D225 - D229 . http://d.old.wanfangdata.com.cn/Periodical/jsjfz200810057 http://d.old.wanfangdata.com.cn/Periodical/jsjfz200810057 , .

G M McGeehan , J D Becherer , R C Jr Bast , C M Boyer , B Champion , K M Connolly , J G Conway , P Furdon , S Karp , S Kidao , A B McElroy , J Nichols , K M Pryzwansky , F Schoenen , L Sekut , A Truesdale , M Verghese , J Warner , J P Ways . Regulation of tumour necrosis factor-α processing by a metalloproteinase inhibitor . Nature , 1994 . 370 ( 6490 ): 558 - 561 . DOI: 10.1038/370558a0 http://doi.org/10.1038/370558a0 .

D S Nascimento , P J B Pereira , M I R Reis , Vale A Do , J Zou , M T Silva , C J Secombes , Santos N M S Dos . Molecular cloning and expression analysis of sea bass( Dicentrarchus labrax L.) tumor necrosis factor-α(TNF-α) . Fish & Shellfish Immunology , 2007 . 23 ( 3 ): 701 - 710 . DOI: 10.1016/j.fsi.2007.02.003 http://doi.org/10.1016/j.fsi.2007.02.003 .

M L Olleros , R Guler , N Corazza , D Vesin , H P Eugster , G Marchal , P Chavarot , C Mueller , I Garcia . Transmembrane TNF induces an efficient cell-mediated immunity and resistance to Mycobacterium bovis bacillus Calmette-Guerin infection in the absence of secreted TNF and lymphotoxin-α . Journal of Immunology , 2002 . 168 ( 7 ): 3 394 - 3 401 . DOI: 10.4049/jimmunol.168.7.3394 http://doi.org/10.4049/jimmunol.168.7.3394 .

M C Ordás , M M Costa , F J Roca , G López-Castejón , V Mulero , J Meseguer , A Figueras , B Novoa . Turbot TNFα gene:molecular characterization and biological activity of the recombinant protein . Molecular Immunology , 2007 . 44 ( 4 ): 389 - 400 . DOI: 10.1016/j.molimm.2006.02.028 http://doi.org/10.1016/j.molimm.2006.02.028 .

M Pasparakis , L Alexopoulou , V Episkopou , G Kollias . Immune and inflammatory responses in TNF α-deficient mice:a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response . Journal of Experimental Medicine , 1996 . 184 ( 4 ): 1 397 - 1 411 . DOI: 10.1084/jem.184.4.1397 http://doi.org/10.1084/jem.184.4.1397 .

D Pennica , G E Nedwin , J S Hayflick , P H Seeburg , R Derynck , M A Palladino , W J Kohr , B B Aggarwal , D V Goeddel . Human tumour necrosis factor:precursor structure, expression and homology to lymphotoxin . Nature , 1984 . 312 ( 5996 ): 724 - 729 . DOI: 10.1038/312724a0 http://doi.org/10.1038/312724a0 .

D M Power , L Llewellyn , M Faustino , M A Nowell , B T Björnsson , I E Einarsdottir , A V M Canario , G E Sweeney . Thyroid hormones in growth and development of fish . Comparative Biochemistry and Physiology Part C:Toxicology & Pharmacology , 2001 . 130 ( 4 ): 447 - 459 . http://cn.bing.com/academic/profile?id=45c30a47acce48752a77a6f2c95b23b7&encoded=0&v=paper_preview&mkt=zh-cn http://cn.bing.com/academic/profile?id=45c30a47acce48752a77a6f2c95b23b7&encoded=0&v=paper_preview&mkt=zh-cn , .

K Praveen , D L Evans , L Jaso-Friedmann . Constitutive expression of tumor necrosis factor-alpha in cytotoxic cells of teleosts and its role in regulation of cell-mediated cytotoxicity . Molecular Immunology , 2006 . 43 ( 3 ): 279 - 291 . DOI: 10.1016/j.molimm.2005.01.012 http://doi.org/10.1016/j.molimm.2005.01.012 .

P Z Qi , C X Xie , B Y Guo , C W Wu . Dissecting the role of transforming growth factor-β1 in topmouth culter immunobiological activity:a fundamental functional analysis . Scientific Reports , 2016 . 6 27179 DOI: 10.1038/srep27179 http://doi.org/10.1038/srep27179 .

L Rink , H Kirchner . Recent progress in the tumor necrosis factor-α field . International Archives of Allergy and Immunology , 1996 . 111 ( 3 ): 199 - 209 . DOI: 10.1159/000237369 http://doi.org/10.1159/000237369 .

F J Roca , I Mulero , A López-Muñoz , M P Sepulcre , S A Renshaw , J Meseguer , V Mulero . Evolution of the inflammatory response in vertebrates:fish TNF-α is a powerful activator of endothelial cells but hardly activates phagocytes . Journal of Immunology , 2008 . 181 ( 7 ): 5 071 - 5 081 . DOI: 10.4049/jimmunol.181.7.5071 http://doi.org/10.4049/jimmunol.181.7.5071 .

A B Sachs . Messenger RNA degradation in eukaryotes . Cell , 1993 . 74 ( 3 ): 413 - 421 . DOI: 10.1016/0092-8674(93)80043-E http://doi.org/10.1016/0092-8674(93)80043-E .

J P J Saeij , R J M Stet , B J De Vries , W B Van Muiswinkel , G F Wiegertjes . Molecular and functional characterization of carp TNF:a link between TNF polymorphism and trypanotolerance . Developmental and Comparative Immunology , 2003 . 27 ( 1 ): 29 - 41 . DOI: 10.1016/S0145-305X(02)00064-2 http://doi.org/10.1016/S0145-305X(02)00064-2 .

B M Saunders , S Tran , S Ruuls , J D Sedgwick , H Briscoe , W J Britton . Transmembrane TNF is sufficient to initiate cell migration and granuloma formation and provide acute, but not long-term, control of Mycobacterium tuberculosis infection . Journal of Immunology , 2005 . 174 ( 8 ): 4 852 - 4 859 . DOI: 10.4049/jimmunol.174.8.4852 http://doi.org/10.4049/jimmunol.174.8.4852 .

R Savan , M Sakai . Presence of multiple isoforms of TNF alpha in carp ( Cyprinus carpio L.):genomic and expression analysis . Fish & Shellfish Immunology , 2004 . 17 ( 1 ): 87 - 94 . http://d.old.wanfangdata.com.cn/NSTLQK/10.1016-j.fsi.2003.11.001/ http://d.old.wanfangdata.com.cn/NSTLQK/10.1016-j.fsi.2003.11.001/ , .

B Sherry , A Cerami . Cachectin/tumor necrosis factor exerts endocrine, paracrine, and autocrine control of inflammatory responses . Journal of Cell Biology , 1988 . 107 ( 4 ): 1 269 - 1 277 . DOI: 10.1083/jcb.107.4.1269 http://doi.org/10.1083/jcb.107.4.1269 .

S J Singer . The structure and insertion of integral proteins in membranes . Annual Review of Cell Biology , 1990 . 6 247 - 296 . DOI: 10.1146/annurev.cb.06.110190.001335 http://doi.org/10.1146/annurev.cb.06.110190.001335 .

M Teles , S Mackenzie , S Boltaña , A Callol , L Tort . Gene expression and TNF-alpha secretion profile in rainbow trout macrophages following exposures to copper and bacterial lipopolysaccharide . Fish & Shellfish Immunology , 2011 . 30 ( 1 ): 340 - 346 . http://d.old.wanfangdata.com.cn/NSTLQK/10.1016-j.fsi.2010.11.006/ http://d.old.wanfangdata.com.cn/NSTLQK/10.1016-j.fsi.2010.11.006/ , .

K T Uysal , S M Wiesbrock , M W Marino , G S Hotamisligil . Protection from obesity-induced insulin resistance in mice lacking TNF-α function . Nature , 1997 . 389 ( 6651 ): 610 - 614 . DOI: 10.1038/39335 http://doi.org/10.1038/39335 .

Y S Wang , L Z Bu , L L Yang , H Y Li , S C Zhang . Identification and functional characterization of fish-egg lectin in zebrafish . Fish & Shellfish Immunology , 2016 . 52 23 - 30 . http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=57fe5822c8b1153db2965d8f857c5e36 http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=57fe5822c8b1153db2965d8f857c5e36 , .

M A Wride , E J Sanders . Potential roles for tumour necrosis factor α during embryonic development . Anatomy and Embryology , 1995 . 191 ( 1 ): 1 - 10 . DOI: 10.1007/bf00215292 http://doi.org/10.1007/bf00215292 .

J Xiao , Z C Zhou , C Chen , W L Huo , Z X Yin , S P Weng , S M Chan , X Q Yu , J G He . Tumor necrosis factor-alpha gene from mandarin fish, Siniperca chuatsi :Molecular cloning, cytotoxicity analysis and expression profile . Molecular Immunology , 2007 . 44 ( 14 ): 3 615 - 3 622 . DOI: 10.1016/j.molimm.2007.03.016 http://doi.org/10.1016/j.molimm.2007.03.016 .

Y J Xu , X Z Liu , M J Liao , H P Wang , Q Y Wang . Molecular cloning and differential expression of three GnRH genes during ovarian maturation of spotted halibut, Verasper variegatus . Journal of Experimental Zoology, Part A, Ecological Genetics and Physiology , 2012 . 317 ( 7 ): 434 - 446 . DOI: 10.1002/jez.1736 http://doi.org/10.1002/jez.1736 .

K Yamano , K Araki , K Sekikawa , Y Inui . Cloning of thyroid hormone receptor genes expressed in metamorphosing flounder . Developmental Genetics , 1994 . 15 ( 4 ): 378 - 382 . DOI: 10.1002/dvg.1020150409 http://doi.org/10.1002/dvg.1020150409 .

K Yamano , S Miwa . Differential gene expression of thyroid hormone receptor α and β in fish development . General and Comparative Endocrinology , 1998 . 109 ( 1 ): 75 - 85 . DOI: 10.1006/gcen.1997.7011 http://doi.org/10.1006/gcen.1997.7011 .

A Y Zhang , D Y Chen , H Wei , L Y Du , T Q Zhao , X Y Wang , H Zhou . Functional characterization of TNF-α in grass carp head kidney leukocytes:Induction and involvement in the regulation of NF-κB signaling . Fish & Shellfish Immunology , 2012 . 33 ( 5 ): 1 123 - 1 132 . .

Z X Zhou , B C Zhang , L Sun . Poly(I:C) induces antiviral immune responses in Japanese flounder ( Paralichthys olivaceus ) that require TLR3 and MDA5 and is negatively regulated by Myd88 . PLoS One , 2014 . 9 ( 11 ): e112918 DOI: 10.1371/journal.pone.0112918 http://doi.org/10.1371/journal.pone.0112918 .

J Zou , C J Secombes , S Long , N Miller , L W Clem , V G Chinchar . Molecular identification and expression analysis of tumor necrosis factor in channel catfish( Ictalurus punctatus ) . Developmental & Comparative Immunology , 2003 . 27 ( 10 ): 845 - 858 . http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=121733170d2727f8a267b8dc43199c07 http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=121733170d2727f8a267b8dc43199c07 , .

J Zou , T Wang , I Hirono , T Aoki , H Inagawa , T Honda , G Soma , M Ototake , T Nakanishi , A E Ellis , C J Secombes . Differential expression of two tumor necrosis factor genes in rainbow trout, Oncorhynchus mykiss . Developmental & Comparative Immunology , 2002 . 26 ( 2 ): 161 - 172 . http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=af281d4ec3c98a0dc9ff807e564963ef http://www.wanfangdata.com.cn/details/detail.do?_type=perio&id=af281d4ec3c98a0dc9ff807e564963ef , .

Views

Downloads

CSCD

Alert me when the article has been cited

Submit

Tools

Publicity Resources

Metabolomics provide novel insights into the settlement and metamorphosis of the scyphozoan jellyfish Aurelia coerulea

Oyster studies reveal the duplication and functional diversification of Bivalvia caspase-8 genes

Inductive effect of bioactive substances on strobilation of jellyfish Aurelia coerulea

The roles of thyroid hormone receptor and T3 in metamorphosis of Haliotis diversicolor

Parametric Model of Lubricant Particle Trajectory inAnnulus Inter-Spools

Related Author

Yanying ZHANG

Shuai LIU

Xiaoyu TANG

Xuerui LIU

Rui ZHANG

Xiangrui GUO

Zhen YU

Ye ZHAO

Related Institution

CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology

School of Ocean, Yantai University

University of Chinese Academy of Sciences

CAS and Shandong Province Key Laboratory of Experimental Marine Biology, Center for Ocean Mega-Science, Institute of Oceanology, Chinese Academy of Sciences

Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology

Address：Editorial Office of JOL, 88 Haijun Rd. Qingdao, 266000, China
Tel：+86-532-82898754 Email：jol@qdio.ac.cn
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备09064830号-19 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰

Tumor necrosis factor-alpha (TNF-α) in spotted halibut Verasper variegatus at the embryonic and metamorphic stages

DOI：10.1007/s00343-019-8289-4

摘要

Abstract

关键词

Keywords

references