Genome-wide characterization of <italic style="font-style: italic">mapk</italic> gene family in black rockfish <italic style="font-style: italic">Sebastes schlegelii </italic>and their expression patterns against <italic style="font-style: italic">Edwardsiella piscicida </italic>infection

Xiaoyan ZHANG; Yuan TIAN; Haohui YU; Min CAO; Chao LI

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Genome-wide characterization of mapk gene family in black rockfish Sebastes schlegelii and their expression patterns against Edwardsiella piscicida infection

Biology | Updated：2024-10-12

- Genome-wide characterization of mapk gene family in black rockfish Sebastes schlegelii and their expression patterns against Edwardsiella piscicida infection
- Journal of Oceanology and Limnology Vol. 41, Issue 6, Pages: 2348-2362(2023)
- Affiliations：
  
  1. School of Marine Science and Engineering, Qingdao Agricultural University, Qingdao 266109, China
  2. Key Laboratory of Mariculture (Ocean University of China), Ministry of Education, Ocean University of China, Qingdao 266003, China
- Author bio：
  
  chaoli@qau.edu.cn
- Funds：
- DOI：
  CLC：
- Received：15 September 2022，
  
  Accepted：01 November 2022，
  
  Online First：16 November 2022，
  
  Published：01 November 2023
- Accepted：
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ZHANG Xiaoyan,TIAN Yuan,YU Haohui,et al.Genome-wide characterization of mapk gene family in black rockfish Sebastes schlegelii and their expression patterns against Edwardsiella piscicida infection[J].Journal of Oceanology and Limnology,2023,41(06):2348-2362.
DOI：

ZHANG Xiaoyan,TIAN Yuan,YU Haohui,et al.Genome-wide characterization of mapk gene family in black rockfish Sebastes schlegelii and their expression patterns against Edwardsiella piscicida infection[J].Journal of Oceanology and Limnology,2023,41(06):2348-2362. DOI：

摘要

Abstract

Mitogen-activated protein kinases (MAPKs) play pivotal roles in response to environmental stresses and bacterial infections. Compared with those in the higher vertebrates

studies of

mapk

gene family are still limited in teleost. Identification

characterization

classification

and expression profiling of totally 15

mapk

genes in black rockfish (

Sebastes schlegelii

) were conducted. Phylogenetic relationships show that these

mapk

genes could be divided into extracellular signal-regulated kinase (ERK)

c-Jun N-terminal kinase (JNK)

and p38 sub-families. In addition

gene structures

syntenic analysis

and selective pressure analysis are performed to confirm their annotations. Results of selective pressure analysis indicate that

mapk1

mapk3

mapk7

mapk10

mapk11

and

mapk12

underwent significantly-positive selections

while the others genes such as

mapk4

mapk6

mapk15

mapk8a

mapk8b

mapk9

mapk13

mapk14a

and

mapk14b

were under purifying

selections. Moreover

results of qRT-PCR indicate that

mapk

genes in 8 healthy tissues displayed different expression patterns. The expression patterns of several

mapk

genes including

mapk12

mapk13

mapk14a

mapk14b

and

mapk15

were significantly changed in mucosal tissues after

Edwardsiella piscicida

infection. This study demonstrates that

mapk

genes in black rockfish play vital prevention roles against bacterial infection

which not only helps us understand the structure and function of

mapk

genes in black rockfish

but also provides a reference to understand the role of

mapk

genes in teleost immune responses.

关键词

Keywords

references

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Related Author

Xu YAN

Qiang FU

Ning YANG

Ningning WANG

Lin SONG

Bin WANG

Bao SHI

Yan JIANG

Related Institution

College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology

Key Laboratory of Sustainable Development of Marine Fisheries, Ministry of Agriculture and Rural Affairs, Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences

Laboratory for Marine Fisheries and Food Production Processes, Pilot National Laboratory for Marine Science and Technology(Qingdao)

College of Pharmacy, Binzhou Medical University

College of Life Science, Yantai University

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Genome-wide characterization of mapk gene family in black rockfish Sebastes schlegelii and their expression patterns against Edwardsiella piscicida infection

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