Discovery of prenylated indole alkaloid and natural xanthone from cold-seep sediment derived fungus <italic style="font-style: italic">Talaromyces funiculosus</italic> SD-523

Yanan WANG; Xiaoming LI; Fengyi LÜ; Suiqun YANG; Linghong MENG; Bingui WANG

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Discovery of prenylated indole alkaloid and natural xanthone from cold-seep sediment derived fungus Talaromyces funiculosus SD-523

Biology | Updated：2024-10-12

- Discovery of prenylated indole alkaloid and natural xanthone from cold-seep sediment derived fungus Talaromyces funiculosus SD-523
- Journal of Oceanology and Limnology Vol. 41, Issue 3, Pages: 1152-1158(2023)
- Affiliations：
  
  1.CAS and Shandong Province Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China
  2.College of Marine Science, University of Chinese Academy of Sciences, Beijing 100049, China
  3.Laboratory of Marine Biology and Biotechnology, Pilot National Laboratory for Marine Science and Technology (Qingdao), Qingdao 266237, China
  4.Center for Ocean Mega-Science, Chinese Academy of Sciences, Qingdao 266071, China
- Author bio：
  
  menglh@qdio.ac.cn
  wangbg@qdio.ac.cn
- Funds：
- DOI：
  CLC：
- Received：05 February 2022，
  
  Published：01 May 2023
- Accepted：
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WANG Yanan,LI Xiaoming,LÜ Fengyi,et al.Discovery of prenylated indole alkaloid and natural xanthone from cold-seep sediment derived fungus Talaromyces funiculosus SD-523[J].Journal of Oceanology and Limnology,2023,41(03):1152-1158.
DOI：

WANG Yanan,LI Xiaoming,LÜ Fengyi,et al.Discovery of prenylated indole alkaloid and natural xanthone from cold-seep sediment derived fungus Talaromyces funiculosus SD-523[J].Journal of Oceanology and Limnology,2023,41(03):1152-1158. DOI：

摘要

Abstract

A new prenylated indole alkaloid 11

17-

epi

-mangrovamide A (

)

a new natural occurring product

7-dihydroxy-6-methyl-8-hydroxymethyl-xanthone (

)

two known alkaloids

mangrovamide A (

) and mangrovamide G (

)

and four known polyketide derivatives (

5‍

–

‍8

) were isolated and identified from the cold-seep sediment derived fungal strain

Talaromyces funiculosus

SD-523. Their structures were elucidated by combination of nuclear magnetic resonance (NMR)

high resolution electrospray ionization mass spectroscopy (HRESIMS)

quantum chemical electronic circular dichroism (ECD)

and DP4+ probability analysis as well as by comparison of the data with literature reports. All isolated compounds were tested for antibacteria

l activities.

关键词

Keywords

references

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Related Institution

Center for Ocean Mega-Science, Chinese Academy of Sciences

Laboratory for Marine Mineral Resources, Laoshan Laboratory

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Discovery of prenylated indole alkaloid and natural xanthone from cold-seep sediment derived fungus Talaromyces funiculosus SD-523

DOI：

摘要

Abstract

关键词

Keywords

references